Radiation oncology in the era of precision medicine

M Baumann, M Krause, J Overgaard, J Debus… - Nature Reviews …, 2016 - nature.com
Technological advances and clinical research over the past few decades have given
radiation oncologists the capability to personalize treatments for accurate delivery of …

Adaptive radiotherapy for anatomical changes

JJ Sonke, M Aznar, C Rasch - Seminars in radiation oncology, 2019 - Elsevier
The anatomy of cancer patients changes between radiation treatment planning and delivery
as well as over the course of radiotherapy. Adaptive radiotherapy (ART) aims to deliver …

Use of normal tissue complication probability models in the clinic

LB Marks, ED Yorke, A Jackson, RK Ten Haken… - International Journal of …, 2010 - Elsevier
The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review
summarizes the currently available three-dimensional dose/volume/outcome data to update …

Image-guided radiotherapy: from current concept to future perspectives

DA Jaffray - Nature reviews Clinical oncology, 2012 - nature.com
Radiotherapy is a highly effective, targeted therapy for the management of cancer.
Technological innovations have enabled the direct integration of imaging technology into …

Radiation dose–volume effects in the brain

YR Lawrence, XA Li, I El Naqa, CA Hahn… - International Journal of …, 2010 - Elsevier
We have reviewed the published data regarding radiotherapy (RT)-induced brain injury.
Radiation necrosis appears a median of 1–2 years after RT; however, cognitive decline …

kV-Cone-beam-CT-basierte bildgeführte Strahlentherapie–ein klinischer Überblick: A Clinical Review

J Boda-Heggemann, F Lohr, F Wenz, M Flentje… - Strahlentherapie und …, 2011 - Springer
Abstract Aims and Methods: Delivery of high radiation doses while simultaneously sparing
organs at risk requires advanced imaging for target volume definition, highly conformal dose …

AAPM Task Group 264: The safe clinical implementation of MLC tracking in radiotherapy

PJ Keall, A Sawant, RI Berbeco, JT Booth… - Medical …, 2021 - Wiley Online Library
The era of real‐time radiotherapy is upon us. Robotic and gimbaled linac tracking are
clinically established technologies with the clinical realization of couch tracking in …

A review of the clinical evidence for intensity-modulated radiotherapy

J Staffurth - Clinical oncology, 2010 - Elsevier
AIMS: Intensity-modulated radiotherapy (IMRT) is a development of three-dimensional
conformal radiotherapy that offers improvements in dosimetry in many clinical scenarios …

Accuracy required and achievable in radiotherapy dosimetry: have modern technology and techniques changed our views?

D Thwaites - Journal of Physics: Conference Series, 2013 - iopscience.iop.org
In this review of the accuracy required and achievable in radiotherapy dosimetry, older
approaches and evidence-based estimates for 3DCRT have been reprised, summarising …

Improvement in toxicity in high risk prostate cancer patients treated with image-guided intensity-modulated radiotherapy compared to 3D conformal radiotherapy …

J Sveistrup, PM af Rosenschöld, JO Deasy, JH Oh… - Radiation …, 2014 - Springer
Background Image-guided radiotherapy (IGRT) facilitates the delivery of a very precise
radiation dose. In this study we compare the toxicity and biochemical progression-free …