RNA-binding proteins in cancer: old players and new actors
RNA-binding proteins (RBPs) are key players in post-transcriptional events. The
combination of versatility of their RNA-binding domains with structural flexibility enables …
combination of versatility of their RNA-binding domains with structural flexibility enables …
RNA-binding proteins and cancer metastasis
S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …
RNA-binding proteins hold key roles in function, dysfunction, and disease
S Kelaini, C Chan, VA Cornelius, A Margariti - Biology, 2021 - mdpi.com
Simple Summary Chronic hyperglycemia manifests in a variety of different micro-and
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …
macrovascular disorders such as diabetes mellitus and cardiovascular disease and has …
[HTML][HTML] RNA binding protein as an emerging therapeutic target for cancer prevention and treatment
S Hong - Journal of cancer prevention, 2017 - ncbi.nlm.nih.gov
After transcription, RNAs are always associated with RNA binding proteins (RBPs) to
perform biological activities. RBPs can interact with target RNAs in sequence-and structure …
perform biological activities. RBPs can interact with target RNAs in sequence-and structure …
Immune-related long non-coding RNA signature identified prognosis and immunotherapeutic efficiency in bladder cancer (BLCA)
Background As bladder cancer was recognized to be immunogenic, dozens of studies have
focused on immune biology of BLCA, but little is known about its relationship with the long …
focused on immune biology of BLCA, but little is known about its relationship with the long …
Delivery of CRISPR-Cas9 system for screening and editing RNA binding proteins in cancer
RNA-binding proteins (RBPs) play an important role in RNA metabolism, regulating the
stability, localization, and functional dynamics of RNAs. Alternation in the RBP-RNA network …
stability, localization, and functional dynamics of RNAs. Alternation in the RBP-RNA network …
Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma
BR Correa, PR de Araujo, M Qiao, SC Burns, C Chen… - Genome Biology, 2016 - Springer
Background Glioblastoma (GBM) is the most common and aggressive type of brain tumor.
Currently, GBM has an extremely poor outcome and there is no effective treatment. In this …
Currently, GBM has an extremely poor outcome and there is no effective treatment. In this …
Proteomics-based identification of dysregulated proteins in breast cancer
Immunohistochemistry (IHC) is still widely used as a morphology-based assay for in situ
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
analysis of target proteins as specific tumor antigens. However, as a very heterogeneous …
Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells
ABSTRACT RNA binding proteins have emerged as critical oncogenic factors and potential
targets in cancer therapy. In this study, we evaluated Musashi1 (Msi1) targeting as a strategy …
targets in cancer therapy. In this study, we evaluated Musashi1 (Msi1) targeting as a strategy …
RNA-binding protein FXR1 regulates p21 and TERC RNA to bypass p53-mediated cellular senescence in OSCC
RNA-binding proteins (RBP) regulate numerous aspects of co-and post-transcriptional gene
expression in cancer cells. Here, we demonstrate that RBP, fragile X-related protein 1 …
expression in cancer cells. Here, we demonstrate that RBP, fragile X-related protein 1 …