[HTML][HTML] Understanding stress: Insights from rodent models

F Atrooz, KA Alkadhi, S Salim - Current research in neurobiology, 2021 - Elsevier
Through incorporating both physical and psychological forms of stressors, a variety of rodent
models have provided important insights into the understanding of stress physiology …

Neurobiology of chronic mild stress: parallels to major depression

MN Hill, KGC Hellemans, P Verma, BB Gorzalka… - Neuroscience & …, 2012 - Elsevier
The chronic mild (or unpredictable/variable) stress (CMS) model was developed as an
animal model of depression more than 20 years ago. The foundation of this model was that …

Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: comorbidity between depression and neurodegenerative disorders

H Anisman, Z Merali, S Hayley - Progress in neurobiology, 2008 - Elsevier
Given the array of biological changes induced by stressors, it is not surprising that these
experiences may provoke a variety of illnesses. Among others things, stressors promote …

Neuroimmune mechanisms of cytokine-induced depression: current theories and novel treatment strategies

JM Loftis, M Huckans, BJ Morasco - Neurobiology of disease, 2010 - Elsevier
The relationships between immune and neural function are an increasingly important area
of study for neuropsychiatric disorders, in particular depression. This is exemplified by the …

The clinical implications of mouse models of enhanced anxiety

SB Sartori, R Landgraf, N Singewald - Future neurology, 2011 - Taylor & Francis
Mice are increasingly overtaking the rat model organism in important aspects of anxiety
research, including drug development. However, translating the results obtained in mouse …

Synergistic and additive actions of a psychosocial stressor and endotoxin challenge: circulating and brain cytokines, plasma corticosterone and behavioral changes in …

J Gibb, S Hayley, R Gandhi, MO Poulter… - Brain, behavior, and …, 2008 - Elsevier
Activation of the inflammatory immune response may provoke neuroendocrine and central
neurochemical effects that are reminiscent of those elicited by traditional stressors, and …

Effects of short-term fasting in male Sprague–Dawley rats

MH Nowland, K Hugunin, KL Rogers - Comparative Medicine, 2011 - ingentaconnect.com
Fasting is a common procedure for animals in experiments. Although fasting may be
necessary for scientific reasons, it should be minimized. In the current study, jugular …

Sex-biased stress signaling: the corticotropin-releasing factor receptor as a model

RJ Valentino, D Bangasser, EJ Van Bockstaele - Molecular pharmacology, 2013 - Elsevier
Sex differences in the prevalence or severity of many diseases and in the response to
pharmacological agents are well recognized. Elucidating the biologic bases of these …

Effects of stressors and immune activating agents on peripheral and central cytokines in mouse strains that differ in stressor responsivity

J Gibb, S Hayley, MO Poulter, H Anisman - Brain, behavior, and immunity, 2011 - Elsevier
The impact of inflammatory immune activation on behavioral and physiological processes
varies with antecedent stressor experiences. We assessed whether immune activation …