Lipopolysaccharide (LPS), also referred to as endotoxin, is the major component of Gram-
negative bacteria's outer cell wall. It is one of the main types of pathogen-associated …

The interactions between sugar-containing molecules from the bacteria cell wall and pattern
recognition receptors (PRR) on the plasma membrane or cytosol of specialized host cells …

Fluorescence correlation spectroscopy (FCS) is one of the major biophysical techniques
used for unraveling molecular interactions in vitro and in vivo. It allows minimally invasive …

Liquid-liquid phase separation (LLPS) explains many intracellular activities, but its role in
extracellular functions has not been studied to the same extent. Here we report how LLPS …

Altered intestinal permeability has been correlated with Parkinson's pathophysiology in the
enteric nervous system, before manifestations in the central nervous system (CNS). The …

Abstract Host defense cationic Antimicrobial Peptides (AMPs) can kill microorganisms
including bacteria, viruses and fungi using various modes of action. The negatively charged …

Recently, we reported a pH-responsive nanoparticle (NP) system shelled with chitosan (CS),
which could effectively increase the oral absorption of insulin and produce a hypoglycemic …

Lipopolysaccharide (LPS), the major constituent of the outer membrane of Gram-negative
bacteria, is an important element against permeability of bactericidal agents, including …

Macrocyclic amphiphilic molecules based on calix [4] arenes are highly attractive for
controlled supramolecular assembly of DNA into small nanoparticles, since they present a …

Although nanoparticle-tagged antimicrobal peptides have gained considerable importance
in recent years, their structure–function correlation has not yet been explored. Here, we have …