[HTML][HTML] The role of TGF-β/SMAD4 signaling in cancer
Transforming growth factor β (TGF-β) signaling pathway plays important roles in many
biological processes, including cell growth, differentiation, apoptosis, migration, as well as …
biological processes, including cell growth, differentiation, apoptosis, migration, as well as …
TGF-β signalling from cell membrane to nucleus through SMAD proteins
CH Heldin, K Miyazono, P Ten Dijke - Nature, 1997 - nature.com
The recent identification of the SMAD family of signal transducer proteins has unravelled the
mechanisms by which transforming growth factor-β (TGF-β) signals from the cell membrane …
mechanisms by which transforming growth factor-β (TGF-β) signals from the cell membrane …
[HTML][HTML] Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene
Smad proteins play a key role in the intracellular signalling of transforming growth factor β
(TGFβ), which elicits a large variety of cellular responses. Upon TGFβ receptor activation …
(TGFβ), which elicits a large variety of cellular responses. Upon TGFβ receptor activation …
TGF-β signaling by Smad proteins
K Miyazono - Cytokine & growth factor reviews, 2000 - Elsevier
Smads are signal transducers for the members of the transforming growth factor-β (TGF-β)
superfamily. Bone morphogenetic proteins (BMPs) and their receptors induce differentiation …
superfamily. Bone morphogenetic proteins (BMPs) and their receptors induce differentiation …
Specificity, diversity, and regulation in TGF‐β superfamily signaling
E Piek, CH HELDIN, PTEN DIJKE - The FASEB Journal, 1999 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) superfamily members are multifunctional cell‐cell
signaling proteins that play pivotal roles in tissue homeostasis and development of …
signaling proteins that play pivotal roles in tissue homeostasis and development of …
TGFβ Signaling in Tumor Initiation, Epithelial‐to‐Mesenchymal Transition, and Metastasis
P Papageorgis - Journal of oncology, 2015 - Wiley Online Library
Retaining the delicate balance in cell signaling activity is a prerequisite for the maintenance
of physiological tissue homeostasis. Transforming growth factor‐beta (TGFβ) signaling is an …
of physiological tissue homeostasis. Transforming growth factor‐beta (TGFβ) signaling is an …
Signal transduction by bone morphogenetic proteins
M Kawabata, T Imamura, K Miyazono - Cytokine & growth factor reviews, 1998 - Elsevier
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which are members of
the transforming growth factor-β (TGF-β) superfamily. Activities of BMPs are extracellularly …
the transforming growth factor-β (TGF-β) superfamily. Activities of BMPs are extracellularly …
TβRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling
S Abdollah, M Macı́as-Silva, T Tsukazaki… - Journal of Biological …, 1997 - ASBMB
Mothers against Dpp-related or Smad proteins are essential components of serine/threonine
kinase receptor signaling pathways that are regulated by phosphorylation. Recently, it was …
kinase receptor signaling pathways that are regulated by phosphorylation. Recently, it was …
Role of transforming growth factor-β signaling in cancer
MP de Caestecker, E Piek… - Journal of the National …, 2000 - academic.oup.com
Signaling from transforming growth factor-β (TGF-β) through its unique transmembrane
receptor serine–threonine kinases plays a complex role in carcinogenesis, having both …
receptor serine–threonine kinases plays a complex role in carcinogenesis, having both …
Calcium-independent phospholipases A2 and their roles in biological processes and diseases
Among the family of phospholipases A 2 (PLA 2 s) are the Ca 2+-independent PLA 2 s (iPLA
2 s) and they are designated group VI iPLA 2 s. In relation to secretory and cytosolic PLA 2 s …
2 s) and they are designated group VI iPLA 2 s. In relation to secretory and cytosolic PLA 2 s …