Studies of steroid modifications catalyzed by microbial whole cells represent a well-
established research area in white biotechnology. Still, advances over the last decade in …

Tuberculosis is a distinctive disease in which the causative agent, Mycobacterium
tuberculosis, can persist in humans for decades by avoiding clearance from host immunity …

The pathways that comprise cellular metabolism are highly interconnected, and alterations
in individual enzymes can have far-reaching effects. As a result, global profiling methods …

Pathogenic bacteria have evolved highly specialized systems to extract essential nutrients
from their hosts. Mycobacterium tuberculosis (Mtb) scavenges lipids (cholesterol and fatty …

Steroid-based drugs have been developed as the second largest medical category in
pharmaceutics. The well-established route of steroid industry includes two steps: the …

Mycobacteria possess different type VII secretion (T7S) systems to secrete proteins across
their unusual cell envelope. One of these systems, ESX-5, is only present in slow-growing …

Non-tuberculous mycobacteria (NTM) are paradigmatic colonizers of the total environment,
circulating at the interfaces of the atmosphere, lithosphere, hydrosphere, biosphere, and …

Mycobacterium tuberculosis (Mtb) is an intracellular pathogen that infects 10 million people
worldwide and kills 2 million people every year. The uptake and utilization of nutrients by …

The ability of science and medicine to control the pathogen Mycobacterium tuberculosis
(Mtb) requires an understanding of the complex host environment within which it resides …

Cholesterol is a steroid commonly found in nature with a great relevance in biology,
medicine and chemistry, playing an essential role as a structural component of animal cell …