The year 2011 marked an important transition for FPGA high-level synthesis (HLS), as it
went from prototy** to deployment. A decade later, in this article, we assess the progress …

We now need more than ever to make genome analysis more intelligent. We need to read,
analyze, and interpret our genomes not only quickly, but also accurately and efficiently …

In this paper, we propose BioHD, a novel genomic sequence searching platform based on
Hyper-Dimensional Computing (HDC) for hardware-friendly computation. BioHD transforms …

Read map** is a fundamental step in many genomics applications. It is used to identify
potential matches and differences between fragments (called reads) of a sequenced …

DNA sequencing data continue to progress toward longer reads with increasingly lower
sequencing error rates. We focus on the critical problem of map**, or aligning, low …

Long-read sequencing is now routinely used at scale for genomics and transcriptomics
applications. Map** long reads or a draft genome assembly to a reference sequence is …

Long read sequencing technology is becoming increasingly popular for Precision Medicine
applications like Whole Genome Sequencing (WGS) and microbial abundance estimation …

Background Third-generation nanopore sequencers offer selective sequencing or “Read
Until” that allows genomic reads to be analyzed in real time and abandoned halfway if not …

Despite an increasing adoption of high-level synthesis (HLS) for its design productivity
advantages, there remains a significant gap in the achievable clock frequency between an …

FPGAs have been proven to be powerful computational accelerators across many types of
workloads. The mainstream programming approach is high level synthesis (HLS), which …