Mechanisms of mesenchymal stem/stromal cell function
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …
Legionnaires' Disease: State of the Art Knowledge of Pathogenesis Mechanisms of Legionella
S Mondino, S Schmidt, M Rolando… - Annual Review of …, 2020 - annualreviews.org
Legionella species are environmental gram-negative bacteria able to cause a severe form of
pneumonia in humans known as Legionnaires' disease. Since the identification of …
pneumonia in humans known as Legionnaires' disease. Since the identification of …
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes
Microglia are the CNS resident immune cells that react to misfolded proteins through pattern
recognition receptor ligation and activation of inflammatory pathways. Here, we studied how …
recognition receptor ligation and activation of inflammatory pathways. Here, we studied how …
Mitochondrial transfer via tunneling nanotubes is an important mechanism by which mesenchymal stem cells enhance macrophage phagocytosis in the in vitro and in …
MV Jackson, TJ Morrison, DF Doherty, DF McAuley… - Stem …, 2016 - academic.oup.com
Mesenchymal stromal cells (MSC) have been reported to improve bacterial clearance in
preclinical models of Acute Respiratory Distress Syndrome (ARDS) and sepsis. The …
preclinical models of Acute Respiratory Distress Syndrome (ARDS) and sepsis. The …
[HTML][HTML] Mitochondria on the move: Horizontal mitochondrial transfer in disease and health
Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …
types. This concept was challenged recently when cellular organelles including …
Mitochondria as a therapeutic target for ischemic stroke
Z He, N Ning, Q Zhou, SE Khoshnam… - Free Radical Biology and …, 2020 - Elsevier
Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …
Functional mitochondria in health and disease
The ability to rapidly adapt cellular bioenergetic capabilities to meet rapidly changing
environmental conditions is mandatory for normal cellular function and for cancer …
environmental conditions is mandatory for normal cellular function and for cancer …
Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria
R Chakraborty, T Nonaka, M Hasegawa… - Cell Death & …, 2023 - nature.com
Abstract Tunnelling Nanotubes (TNTs) facilitate contact-mediated intercellular
communication over long distances. Material transfer via TNTs can range from ions and …
communication over long distances. Material transfer via TNTs can range from ions and …
Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells
X Wang, HH Gerdes - Cell Death & Differentiation, 2015 - nature.com
Tunneling nanotubes (TNTs) are F-actin-based membrane tubes that form between cells in
culture and in tissues. They mediate intercellular communication ranging from electrical …
culture and in tissues. They mediate intercellular communication ranging from electrical …
Trophic effects of mesenchymal stem cells in tissue regeneration
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …