Functional DNA–polymer conjugates

CJ Whitfield, M Zhang, P Winterwerber, Y Wu… - Chemical …, 2021 - ACS Publications
DNA nanotechnology has seen large developments over the last 30 years through the
combination of solid phase synthesis and the discovery of DNA nanostructures. Solid phase …

Atom transfer radical polymerization for biorelated hybrid materials

SL Baker, B Kaupbayeva, S Lathwal, SR Das… - …, 2019 - ACS Publications
Proteins, nucleic acids, lipid vesicles, and carbohydrates are the major classes of
biomacromolecules that function to sustain life. Biology also uses post-translation …

RNA-polymer hybrids via direct and site-selective acylation with the ATRP initiator and photoinduced polymerization

J Jeong, X Hu, H Murata, G Szczepaniak… - Journal of the …, 2023 - ACS Publications
Combining synthetic polymers with RNA paves the way for creating RNA-based materials
with non-canonical functions. We have developed an acylation reagent that allows for direct …

DNA-functionalized dye-loaded polymeric nanoparticles: ultrabright FRET platform for amplified detection of nucleic acids

N Melnychuk, AS Klymchenko - Journal of the American Chemical …, 2018 - ACS Publications
Going beyond the limits of optical biosensing motivates exploration of signal amplification
strategies that convert a single molecular recognition event into a response equivalent to …

Expanding the architectural horizon of nucleic-acid-polymer biohybrids by site-controlled incorporation of ATRP initiators in DNA and RNA

J Jeong, G Szczepaniak, SR Das, K Matyjaszewski - Chem, 2023 - cell.com
Modifying biomacromolecules with synthetic polymers has been a powerful approach to
develo** multifunctional hybrid biomaterials for nanoscience and biomedical applications …

DNA–Polymer Nanostructures by RAFT Polymerization and Polymerization‐Induced Self‐Assembly

T Lückerath, K Koynov, S Loescher… - Angewandte Chemie …, 2020 - Wiley Online Library
Nanostructures derived from amphiphilic DNA–polymer conjugates have emerged
prominently due to their rich self‐assembly behavior; however, their synthesis is traditionally …

Programmable polymer materials empowered by DNA nanotechnology

SK Speed, K Gupta, YH Peng… - Journal of Polymer …, 2023 - Wiley Online Library
Over the past century, synthetic polymers have had a transformative impact on human life,
replacing nature‐derived materials in many areas. Yet, despite their many advantages, the …

DNA–polymer conjugates by photoinduced RAFT polymerization

T Lueckerath, T Strauch, K Koynov… - …, 2018 - ACS Publications
Conventional grafting-to approaches to DNA–polymer conjugates are often limited by low
reaction yields due to the sterically hindered coupling of a presynthesized polymer to DNA …

Recent advances in amphiphilic polymer–oligonucleotide nanomaterials via living/controlled polymerization technologies

H Sun, L Yang, MP Thompson, S Schara… - Bioconjugate …, 2019 - ACS Publications
Over the past decade, the field of polymer–oligonucleotide nanomaterials has flourished
because of the development of synthetic techniques, particularly living polymerization …

Modular self-assembly of gamma-modified peptide nucleic acids in organic solvent mixtures

S Kumar, A Pearse, Y Liu, RE Taylor - Nature communications, 2020 - nature.com
Nucleic acid-based materials enable sub-nanometer precision in self-assembly for fields
including biophysics, diagnostics, therapeutics, photonics, and nanofabrication. However …