Leishmaniasis is a neglected tropical disease caused by parasites of the genus Leishmania.
As approved human vaccines are not available, treatment and prevention rely heavily on …

Natural killer (NK) cells have the dual ability to produce pro-inflammatory (IFNγ) and anti-
inflammatory (IL-10) cytokines during systemic infection, which points to their crucial role …

Background Surveillance of human leishmaniasis in Europe is mostly limited to country-
specific information from autochthonous infections in the southern part. As at the end of …

Co-infection among leishmaniasis and other infectious diseases is common among natural
populations especially in the endemic areas of the disease. It depends on the environmental …

Parasites of the genus Leishmania cause a variety of devastating and often fatal diseases in
humans and domestic animals worldwide. The need for new therapeutic strategies is urgent …

Background Trypanosomatids are among the most critical parasites for public health due to
their impact on human, animal, and plant health. Diseases associated with these pathogens …

Leishmaniasis, a neglected tropical disease, still remains a global concern for the
healthcare sector. The primary causative agents of the disease comprise diverse …

Leishmaniasis is a vector-borne disease caused by obligate intracellular protozoan
parasites that can infect humans and other mammals. Pro-and anti-inflammatory cytokines …

The parasites of the genus Leishmania survive and proliferate in the host phagocytic cells by
taking control over their microbicidal functions. The parasite also promotes differentiation of …

Ruxolitinib is a JAK1/2 inhibitor that has revolutionized the approach to myelofibrosis. On the
one side, this drug can rapidly improve the symptoms related to the hematological disease; …