Flavonoids as potential anti-inflammatory molecules: A review
Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits,
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …
Flavonoids as natural anti-inflammatory agents targeting nuclear factor-kappa B (NFκB) signaling in cardiovascular diseases: a mini review
Cardiovascular diseases (CVDs) such as angina, hypertension, myocardial ischemia, and
heart failure are the leading causes of morbidity and mortality worldwide. One of the major …
heart failure are the leading causes of morbidity and mortality worldwide. One of the major …
Carfilzomib-associated cardiovascular adverse events: a systematic review and meta-analysis
Importance Cardiovascular adverse events (CVAE) with carfilzomib in patients with multiple
myeloma can be potentially life-threatening and remain incompletely characterized. We …
myeloma can be potentially life-threatening and remain incompletely characterized. We …
Prospective study of cardiac events during proteasome inhibitor therapy for relapsed multiple myeloma
RF Cornell, B Ky, BM Weiss, CN Dahm… - Journal of clinical …, 2019 - ascopubs.org
PURPOSE Cardiovascular adverse events (CVAEs) can occur during proteasome inhibitor
(PI) therapy. We conducted a prospective, observational, multi-institutional study to define …
(PI) therapy. We conducted a prospective, observational, multi-institutional study to define …
The protective effects of rutin on the liver, kidneys, and heart by counteracting organ toxicity caused by synthetic and natural compounds
Rutin is a flavonoid present in many plant species. Because of its antioxidant, anti‐
inflammatory, and antiapoptotic properties, rutin is of interest for its potential protective …
inflammatory, and antiapoptotic properties, rutin is of interest for its potential protective …
Molecular mechanisms of carfilzomib-induced cardiotoxicity in mice and the emerging cardioprotective role of metformin
P Efentakis, G Kremastiotis, A Varela… - Blood, The Journal …, 2019 - ashpublications.org
Carfilzomib (Cfz), an irreversible proteasome inhibitor licensed for relapsed/refractory
myeloma, is associated with cardiotoxicity in humans. We sought to establish the optimal …
myeloma, is associated with cardiotoxicity in humans. We sought to establish the optimal …
Proteasome inhibitor-related cardiotoxicity: mechanisms, diagnosis, and management
Abstract Purpose of Review Multiple myeloma is the second most common hematologic
malignancy in the USA, with over 32,000 new cases and nearly 13,000 deaths expected in …
malignancy in the USA, with over 32,000 new cases and nearly 13,000 deaths expected in …
NF-κB, A potential therapeutic target in cardiovascular diseases
W Cheng, C Cui, G Liu, C Ye, F Shao… - … Drugs and Therapy, 2023 - Springer
Cardiovascular diseases (CVDs) are the leading cause of death globally. Atherosclerosis is
the basis of major CVDs–myocardial ischemia, heart failure, and stroke. Among numerous …
the basis of major CVDs–myocardial ischemia, heart failure, and stroke. Among numerous …
Chemotherapy induced cardiotoxicity: a state of the art review on general mechanisms, prevention, treatment and recent advances in novel therapeutics
T Abdul-Rahman, A Dunham, H Huang… - Current Problems in …, 2023 - Elsevier
As medicine advances to employ sophisticated anticancer agents to treat a vast array of
oncological conditions, it is worth considering side effects associated with several …
oncological conditions, it is worth considering side effects associated with several …
Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats
Background Cisplatin (CP) is commonly used in the treatment of different types of cancer but
nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study …
nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study …