Integrative physiology of pneumonia

LJ Quinton, AJ Walkey, JP Mizgerd - Physiological reviews, 2018 - journals.physiology.org
Pneumonia is a type of acute lower respiratory infection that is common and severe. The
outcome of lower respiratory infection is determined by the degrees to which immunity is …

Acute phase reactants in infections: evidence-based review and a guide for clinicians

A Markanday - Open forum infectious diseases, 2015 - academic.oup.com
Acute-phase reactants such as erythrocyte sedimentation rate and C-reactive protein have
traditionally been used as markers for inflammation and as a measure of “sickness index” in …

Biomarkers in respiratory tract infections: diagnostic guides to antibiotic prescription, prognostic markers and mediators

M Christ-Crain, B Müller - European Respiratory Journal, 2007 - publications.ersnet.org
Used appropriately, biomarkers improve the assessment of respiratory tract infections and
sepsis. Most prominently, circulating procalcitonin levels increase by a factor of several tens …

[HTML][HTML] Procalcitonin and C-reactive protein in hospitalized adult patients with community-acquired pneumonia or exacerbation of asthma or COPD

M Bafadhel, TW Clark, C Reid, M Medina, S Batham… - Chest, 2011 - Elsevier
Background Antibiotic overuse in respiratory illness is common and is associated with drug
resistance and hospital-acquired infection. Biomarkers that can identify bacterial infections …

Diagnostic value of C reactive protein in infections of the lower respiratory tract: systematic review

V van der Meer, AK Neven, PJ van den Broek… - Bmj, 2005 - bmj.com
Objectives To evaluate the diagnostic accuracy of C reactive protein in detecting
radiologically proved pneumonia and to evaluate how well it can discriminate between …

Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia [ISRCTN04176397]

M Christ-Crain, NG Morgenthaler, D Stolz, C Müller… - Critical Care, 2006 - Springer
Introduction Pro-adrenomedullin (proADM) is helpful for individual risk assessment and
outcome prediction in sepsis. A major cause of sepsis is community-acquired pneumonia …

Biofilm formation avoids complement immunity and phagocytosis of Streptococcus pneumoniae

M Domenech, E Ramos-Sevillano, E García… - Infection and …, 2013 - journals.asm.org
Streptococcus pneumoniae is a frequent member of the microbiota of the human
nasopharynx. Colonization of the nasopharyngeal tract is a first and necessary step in the …

Circulating levels of copeptin, a novel biomarker, in lower respiratory tract infections

B Müller, N Morgenthaler, D Stolz… - European journal of …, 2007 - Wiley Online Library
Background Vasopressin has haemodynamic as well as osmoregulatory effects, and reflects
the individual stress response. Copeptin is cosynthesized with vasopressin, directly …

Distinctive features of severe SARS-CoV-2 pneumonia

GRS Budinger, AV Misharin, KM Ridge… - The Journal of clinical …, 2021 - jci.org
The coronavirus disease 2019 (COVID-19) pandemic is among the most important public
health crises of our generation. Despite the promise of prevention offered by effective …

Biomarkers for predicting short-term mortality in community-acquired pneumonia: A systematic review and meta-analysis

D Viasus, G Del Rio-Pertuz, AF Simonetti… - Journal of Infection, 2016 - Elsevier
Objectives The pneumonia severity index and CURB-65 are risk assessment tools widely
used in community-acquired pneumonia (CAP). However, limitations in these prognostic …