The chemistry of curcumin: from extraction to therapeutic agent
KI Priyadarsini - Molecules, 2014 - mdpi.com
Curcumin, a pigment from turmeric, is one of the very few promising natural products that
has been extensively investigated by researchers from both the biological and chemical …
has been extensively investigated by researchers from both the biological and chemical …
Multitargeting by curcumin as revealed by molecular interaction studies
Covering: up to early 2011 Curcumin (diferuloylmethane), the active ingredient in turmeric
(Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant …
(Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant …
Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for
prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action …
prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action …
Chemical and structural features influencing the biological activity of curcumin
K Indira Priyadarsini - Current pharmaceutical design, 2013 - ingentaconnect.com
Curcumin, a polyphenolic natural product, exhibits therapeutic activity against a number of
diseases, attributed mainly to its chemical structure and unique physical, chemical, and …
diseases, attributed mainly to its chemical structure and unique physical, chemical, and …
Roles of Nrf2 in liver diseases: molecular, pharmacological, and epigenetic aspects
Liver diseases represent a critical health problem with 2 million deaths worldwide per year,
mainly due to cirrhosis and its complications. Oxidative stress plays an important role in the …
mainly due to cirrhosis and its complications. Oxidative stress plays an important role in the …
[HTML][HTML] Antioxidants in liver health
S Casas-Grajales, P Muriel - World journal of gastrointestinal …, 2015 - ncbi.nlm.nih.gov
Liver diseases are a worldwide medical problem because the liver is the principal
detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various …
detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various …
Curcumin, a multifaceted hormetic agent, mediates an intricate crosstalk between mitochondrial turnover, autophagy, and apoptosis
NE Rainey, A Moustapha… - Oxidative Medicine and …, 2020 - Wiley Online Library
Curcumin has extensive therapeutic potential because of its antioxidant, anti‐inflammatory,
and antiproliferative properties. Multiple preclinical studies in vitro and in vivo have proven …
and antiproliferative properties. Multiple preclinical studies in vitro and in vivo have proven …
Protective effect of curcumin (Curcuma longa), against aluminium toxicity: Possible behavioral and biochemical alterations in rats
Aluminium is a potent neurotoxin and has been associated with Alzheimer's disease (AD)
causality for decades. Prolonged aluminium exposure induces oxidative stress and …
causality for decades. Prolonged aluminium exposure induces oxidative stress and …
Radiation-induced liver disease: Beyond DNA damage
YJ Zhou, Y Tang, SJ Liu, PH Zeng, L Qu, QC **g… - Cell Cycle, 2023 - Taylor & Francis
Radiation-induced liver disease (RILD), also known as radiation hepatitis, is a serious side
effect of radiotherapy (RT) for hepatocellular carcinoma. The therapeutic dose of RT can …
effect of radiotherapy (RT) for hepatocellular carcinoma. The therapeutic dose of RT can …
Cadmium‐induced toxicity is rescued by curcumin: a review
Cadmium (Cd) is one of the most common environmental and occupational heavy metals
with extended distribution. Exposure to Cd may be associated with several deleterious …
with extended distribution. Exposure to Cd may be associated with several deleterious …