Protein design: From the aspect of water solubility and stability
Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …
sequence and 3D-conformation. Their manipulation represents important aspects of the …
[HTML][HTML] Metalloproteins containing cytochrome, iron–sulfur, or copper redox centers
Redox reactions play important roles in almost all biological processes, including
photosynthesis and respiration, which are two essential energy processes that sustain all life …
photosynthesis and respiration, which are two essential energy processes that sustain all life …
Protein design: toward functional metalloenzymes
Protein design is a valuable tool for understanding the fundamental factors that dictate
protein structure and function. The field of protein design has seen significant progress over …
protein structure and function. The field of protein design has seen significant progress over …
Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics
Redox potentials are a major contributor in controlling the electron transfer (ET) rates and
thus regulating the ET processes in the bioenergetics. To maximize the efficiency of the ET …
thus regulating the ET processes in the bioenergetics. To maximize the efficiency of the ET …
Protein engineering: the potential of remote mutations
Engineered proteins, especially enzymes, are now commonly used in many industries
owing to their catalytic power, specific binding of ligands, and properties as materials and …
owing to their catalytic power, specific binding of ligands, and properties as materials and …
[HTML][HTML] Design and engineering of photosynthetic light-harvesting and electron transfer using length, time, and energy scales
Decades of research on the physical processes and chemical reaction-pathways in
photosynthetic enzymes have resulted in an extensive database of kinetic information …
photosynthetic enzymes have resulted in an extensive database of kinetic information …
De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex
The de novo design of membrane proteins remains difficult despite recent advances in
understanding the factors that drive membrane protein folding and association. We have …
understanding the factors that drive membrane protein folding and association. We have …
Delineating redox cooperativity in water‐soluble and membrane multiheme cytochromes through protein design
BJ Hardy, P Dubiel, EL Bungay, M Rudin… - Protein …, 2024 - Wiley Online Library
Nature has evolved diverse electron transport proteins and multiprotein assemblies
essential to the generation and transduction of biological energy. However, substantially …
essential to the generation and transduction of biological energy. However, substantially …
Electron transfer across helical peptides
N Amdursky - ChemPlusChem, 2015 - Wiley Online Library
Electron transfer (ET) across proteins is one of the fundamental processes in nature. While
trying to decipher and understand natural ET, much scientific effort has been employed in …
trying to decipher and understand natural ET, much scientific effort has been employed in …
Cellular production of a de novo membrane cytochrome
BJ Hardy, A Martin Hermosilla… - Proceedings of the …, 2023 - National Acad Sciences
Heme-containing integral membrane proteins are at the heart of many bioenergetic
complexes and electron transport chains. The importance of these electron relay hubs …
complexes and electron transport chains. The importance of these electron relay hubs …