High-performance medicine: the convergence of human and artificial intelligence

EJ Topol - Nature medicine, 2019 - nature.com
The use of artificial intelligence, and the deep-learning subtype in particular, has been
enabled by the use of labeled big data, along with markedly enhanced computing power …

Gut microbial metabolites as multi-kingdom intermediates

KA Krautkramer, J Fan, F Bäckhed - Nature Reviews Microbiology, 2021 - nature.com
The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

Gut-liver axis: Pathophysiological concepts and clinical implications

H Tilg, TE Adolph, M Trauner - Cell metabolism, 2022 - cell.com
Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

Role of the gut microbiota in nutrition and health

AM Valdes, J Walter, E Segal, TD Spector - Bmj, 2018 - bmj.com
Role of the gut microbiota in nutrition and health Page 1 36 BMJ 361:Supp1 | the bmj Science
and PoliticS of nutrition Role of the gut microbiota in nutrition and health Ana M Valdes and …

Microbiome-based therapeutics

MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …

DRAM for distilling microbial metabolism to automate the curation of microbiome function

M Shaffer, MA Borton, BB McGivern… - Nucleic acids …, 2020 - academic.oup.com
Microbial and viral communities transform the chemistry of Earth's ecosystems, yet the
specific reactions catalyzed by these biological engines are hard to decode due to the …

You are what you eat: diet, health and the gut microbiota

N Zmora, J Suez, E Elinav - Nature reviews Gastroenterology & …, 2019 - nature.com
Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces sha** the architecture and functionality of resident …

[HTML][HTML] Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance

J Suez, Y Cohen, R Valdés-Mas, U Mor… - Cell, 2022 - cell.com
Non-nutritive sweeteners (NNS) are commonly integrated into human diet and presumed to
be inert; however, animal studies suggest that they may impact the microbiome and …

Host variables confound gut microbiota studies of human disease

I Vujkovic-Cvi**, J Sklar, L Jiang, L Natarajan, R Knight… - Nature, 2020 - nature.com
Low concordance between studies that examine the role of microbiota in human diseases is
a pervasive challenge that limits the capacity to identify causal relationships between host …

Diet–microbiota interactions and personalized nutrition

AA Kolodziejczyk, D Zheng, E Elinav - Nature Reviews Microbiology, 2019 - nature.com
Conceptual scientific and medical advances have led to a recent realization that there may
be no single, one-size-fits-all diet and that differential human responses to dietary inputs …