[HTML][HTML] Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear

TB Lonsdorf, MM Menz, M Andreatta… - Neuroscience & …, 2017 - Elsevier
The so-called 'replicability crisis' has sparked methodological discussions in many areas of
science in general, and in psychology in particular. This has led to recent endeavours to …

Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

TW Robbins, CM Gillan, DG Smith, S de Wit… - Trends in cognitive …, 2012 - cell.com
A key criticism of the main diagnostic tool in psychiatry, the Diagnostic and Statistical Manual
of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we …

Optimizing exposure therapy with an inhibitory retrieval approach and the OptEx Nexus

MG Craske, M Treanor, TD Zbozinek… - Behaviour Research and …, 2022 - Elsevier
Research from recent decades has highlighted the distinction between excitatory and
inhibitory Pavlovian learning mechanisms. Based on this distinction, state-of-the-art …

Maximizing exposure therapy: An inhibitory learning approach

MG Craske, M Treanor, CC Conway, T Zbozinek… - Behaviour research and …, 2014 - Elsevier
Exposure therapy is an effective approach for treating anxiety disorders, although a
substantial number of individuals fail to benefit or experience a return of fear after treatment …

Fear extinction and relapse: state of the art

B Vervliet, MG Craske, D Hermans - Annual review of clinical …, 2013 - annualreviews.org
Exposure-based treatments for clinical anxiety generally are very effective, but relapse is not
uncommon. Likewise, laboratory studies have shown that conditioned fears are easy to …

Rethinking extinction

JE Dunsmoor, Y Niv, N Daw, EA Phelps - Neuron, 2015 - cell.com
Extinction serves as the leading theoretical framework and experimental model to describe
how learned behaviors diminish through absence of anticipated reinforcement. In the past …

Optimizing inhibitory learning during exposure therapy

MG Craske, K Kircanski, M Zelikowsky… - Behaviour research and …, 2008 - Elsevier
Prevailing models of exposure therapy for phobias and anxiety disorders construe level of
fear throughout exposure trials as an index of corrective learning. However, the evidence …

Context and behavioral processes in extinction

ME Bouton - Learning & memory, 2004 - learnmem.cshlp.org
This article provides a selective review and integration of the behavioral literature on
Pavlovian extinction. The first part reviews evidence that extinction does not destroy the …

Context, ambiguity, and unlearning: sources of relapse after behavioral extinction

ME Bouton - Biological psychiatry, 2002 - Elsevier
There is now ample evidence that extinction, the loss of learned performance that occurs
when a Pavlovian signal or an instrumental action is repeatedly presented without its …

Mechanisms of fear extinction

KM Myers, M Davis - Molecular psychiatry, 2007 - nature.com
Excessive fear and anxiety are hallmarks of a variety of disabling anxiety disorders that
affect millions of people throughout the world. Hence, a greater understanding of the brain …