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Lipid metabolism in regulation of macrophage functions
J Yan, T Horng - Trends in cell biology, 2020 - cell.com
Macrophages are cells of the innate immune system that regulate the maintenance of tissue
homeostasis, host defense during pathogen infection, and tissue repair in response to tissue …
homeostasis, host defense during pathogen infection, and tissue repair in response to tissue …
Lipid droplets: platforms with multiple functions in cancer hallmarks
Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production …
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production …
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
Microglia become progressively activated and seemingly dysfunctional with age, and
genetic studies have linked these cells to the pathogenesis of a growing number of …
genetic studies have linked these cells to the pathogenesis of a growing number of …
Lipid droplets and polyunsaturated fatty acid trafficking: Balancing life and death
M Danielli, L Perne, E Jarc Jovičić… - Frontiers in Cell and …, 2023 - frontiersin.org
Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …
Fatty acid metabolism of immune cells: a new target of tumour immunotherapy
S Zhang, K Lv, Z Liu, R Zhao, F Li - Cell death discovery, 2024 - nature.com
Metabolic competition between tumour cells and immune cells for limited nutrients is an
important feature of the tumour microenvironment (TME) and is closely related to the …
important feature of the tumour microenvironment (TME) and is closely related to the …
Nitric oxide in macrophage immunometabolism: hiding in plain sight
Nitric Oxide (NO) is a soluble endogenous gas with various biological functions like
signaling, and working as an effector molecule or metabolic regulator. In response to …
signaling, and working as an effector molecule or metabolic regulator. In response to …
Fatty kidney: emerging role of ectopic lipid in obesity-related renal disease
The global increase in chronic kidney disease (CKD) parallels the obesity epidemic. Obesity
conveys a gradual but independent risk of progression of CKD that seems irrespective of the …
conveys a gradual but independent risk of progression of CKD that seems irrespective of the …
Emerging designs of aggregation-induced emission luminogens for lipid droplets imaging
Lipid droplets (LDs) are organelles that have evolved to store intracellular neutral lipids and
maintain cellular energy homeostasis. Once considered as inert fat particles, they have …
maintain cellular energy homeostasis. Once considered as inert fat particles, they have …
[HTML][HTML] A twist of FATe: Lipid droplets and inflammatory lipid mediators
Lipid droplets are fat storage organelles present in most eukaryotic cells. They consist of a
neutral lipid core containing mostly triglycerides and sterol esters and covered by a …
neutral lipid core containing mostly triglycerides and sterol esters and covered by a …
Not just fat: the structure and function of the lipid droplet
Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …
a surface phospholipid monolayer. Recent studies have revealed many new proteins …