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Risk of bias in studies on prediction models developed using supervised machine learning techniques: systematic review
Objective To assess the methodological quality of studies on prediction models developed
using machine learning techniques across all medical specialties. Design Systematic …
using machine learning techniques across all medical specialties. Design Systematic …
Exercise benefits on Alzheimer's disease: State-of-the-science
PL Valenzuela, A Castillo-García, JS Morales… - Ageing research …, 2020 - Elsevier
Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …
Four distinct trajectories of tau deposition identified in Alzheimer's disease
Alzheimer's disease (AD) is characterized by the spread of tau pathology throughout the
cerebral cortex. This spreading pattern was thought to be fairly consistent across individuals …
cerebral cortex. This spreading pattern was thought to be fairly consistent across individuals …
Artificial intelligence in brain MRI analysis of Alzheimer's disease over the past 12 years: A systematic review
Introduction Multiple structural brain changes in Alzheimer's disease (AD) and mild cognitive
impairment (MCI) have been revealed on magnetic resonance imaging (MRI). There is a fast …
impairment (MCI) have been revealed on magnetic resonance imaging (MRI). There is a fast …
A multiomics approach to heterogeneity in Alzheimer's disease: focused review and roadmap
Aetiological and clinical heterogeneity is increasingly recognized as a common
characteristic of Alzheimer's disease and related dementias. This heterogeneity complicates …
characteristic of Alzheimer's disease and related dementias. This heterogeneity complicates …
Electrochemical biosensor for point-of-care testing of low-abundance biomarkers of neurological diseases
Z Huang, L Zhang, Y Dou, X Liu, S Song… - Analytical …, 2024 - ACS Publications
The neurofilament protein light chain (NEFL) is a potential biomarker of neurodegenerative
diseases, and interleukin-6 (IL-6) is also closely related to neuroinflammation. Especially …
diseases, and interleukin-6 (IL-6) is also closely related to neuroinflammation. Especially …
A high-generalizability machine learning framework for predicting the progression of Alzheimer's disease using limited data
C Wang, Y Li, Y Tsuboshita, T Sakurai, T Goto… - NPJ digital …, 2022 - nature.com
Alzheimer's disease is a neurodegenerative disease that imposes a substantial financial
burden on society. A number of machine learning studies have been conducted to predict …
burden on society. A number of machine learning studies have been conducted to predict …
The road to personalized medicine in Alzheimer's disease: The use of artificial intelligence
A Silva-Spínola, I Baldeiras, JP Arrais, I Santana - Biomedicines, 2022 - mdpi.com
Dementia remains an extremely prevalent syndrome among older people and represents a
major cause of disability and dependency. Alzheimer's disease (AD) accounts for the …
major cause of disability and dependency. Alzheimer's disease (AD) accounts for the …
Subty** of mild cognitive impairment using a deep learning model based on brain atrophy patterns
Trajectories of cognitive decline vary considerably among individuals with mild cognitive
impairment (MCI). To address this heterogeneity, subty** approaches have been …
impairment (MCI). To address this heterogeneity, subty** approaches have been …
Improving Alzheimer diagnoses with an interpretable deep learning framework: Including neuropsychiatric symptoms
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by the
progressive cognitive decline. Among the various clinical symptoms, neuropsychiatric …
progressive cognitive decline. Among the various clinical symptoms, neuropsychiatric …