Understanding how individual neurons integrate the thousands of synaptic inputs they
receive is critical to understanding how the brain works. Modeling studies in silico and …

This article reviews the electroresponsive properties of single neurons in the mammalian
central nervous system (CNS). In some of these cells the ionic conductances responsible for …

A detailed theory of cerebellar cortex is proposed whose consequence is that the
cerebellum learns to perform motor skills. Two forms of input-output relation are described …

It is widely recognized that the neural basis of brain function can be fully understood only by
integrating many disciplines at many levels. Studies of synaptic organization are bringing …

Many of our daily activities, such as riding a bike to work or reading a book in a noisy cafe,
and highly skilled activities, such as a professional playing a tennis match or a violin …

Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle
contraction, neuronal communication, hormone release, cell division, and gene …

Communication between neurons in the brain occurs primarily through synapses made onto
elaborate treelike structures called dendrites. New electrical and optical recording …

The ionic requirements for electro‐responsiveness in thalamic neurones were studied using
in vitro slice preparations of the guinea‐pig diencephalon. Analysis of the current‐voltage …

1. Intradendritic recordings from Purkinje cells in vitro indicate that white matter stimulation
produces large synaptic responses by the activation of the climbing fibre afferent, but …

1. The electrical activity of Purkinje cells was studied in guinea‐pig cerebellar slices in vitro.
Intracellular recordings from Purkinje cell somata were obtained under direct vision, and …