Bis-and trisindolylmethanes (BIMs and TIMs)

M Shiri, MA Zolfigol, HG Kruger… - Chemical …, 2010 - ACS Publications
The indole ring system is present in many natural products, pharmaceuticals,
agrochemicals, and other compounds of importance. 1–8 The indole unit forms the basis for …

More sustainable approaches for the synthesis of N-based heterocycles

NR Candeias, LC Branco, PMP Gois… - Chemical …, 2009 - ACS Publications
More Sustainable Approaches for the Synthesis of N-Based Heterocycles | Chemical
Reviews Recently Viewedclose modal ACS ACS Publications C&EN CAS Find my …

Ionic Liquid 3-Methyl-1-sulfonic Acid Imidazolium Chloride as a Novel and Highly Efficient Catalyst for the Very Rapid Synthesis of bis(Indolyl)methanes under …

MA Zolfigol, A Khazaei, AR Moosavi-Zare… - Organic Preparations …, 2010 - Taylor & Francis
The exploitation of ionic liquids as solvents in organic transformations has been reported
extensively during the past decade. 1–5 The most useful properties of ionic liquids are the …

Recent Developments on the Synthesis of Biologically Significant bis/tris(indolyl)methanes under Various Reaction Conditions: A Review

A Singh, G Kaur, B Banerjee - Current Organic Chemistry, 2020 - benthamdirect.com
Bis (indolyl) methane skeleton is the main building block of many naturally occurring
bioactive compounds. Bis (indolyl) methanes are found to possess a wide range of …

Unmodified 'chitosan in water'as an efficient and recyclable heterogeneous catalytic system for the synthesis of bis (indolyl) methanes

N Taya, J Agarwal - Applied Catalysis A: General, 2024 - Elsevier
A simple, highly efficient and environment friendly method has been developed for the
synthesis of bis (indolyl) methanes using chitosan in aqueous medium. The use of …

Synthesis, in-silico potential enzymatic target predictions, pharmacokinetics, toxicity, anti-microbial and anti-inflammatory studies of bis-(2-methylindolyl) methane …

DT Nagre, SN Mali, BR Thorat, SA Thorat… - Current Enzyme …, 2021 - ingentaconnect.com
Background: The bis (indolyl) methanes (BIMs) scaffold is reported for wide varieties of
pharmacological profiles, including antibacterial, anti-proliferative, anticancer, cytotoxic …

A practical and efficient synthesis of bis (indolyl) methanes in water, and synthesis of di-, tri-, and tetra (bis-indolyl) methanes under thermal conditions catalyzed by …

R Ghorbani-Vaghei, H Veisi, H Keypour… - Molecular …, 2010 - Springer
A simple, clean, and highly efficient green protocol has been developed for synthesis of bis
(indolyl), di (bis-indolyl), and tris-indolyl methanes by the reaction of indole with aldehydes …

Development of Brönsted–Lewis acidic solid catalytic system of 3-methyl-1-sulfonic acid imidazolium transition metal chlorides for the preparation of bis (indolyl) …

P Gogoi, AK Dutta, P Sarma, R Borah - Applied Catalysis A: General, 2015 - Elsevier
Three new heterogeneous catalysts of 3-methyl-1-sulfonic acid imidazolium transition metal
chlorides [Msim][X](where X=[FeCl 4]−,[ZnCl 3]−,[CuCl 2]−) were synthesized containing …

[HTML][HTML] ProHSO4: An efficient catalyst for solvent-free synthesis of bis (indolyl) methanes and their in silico screening for potential biological activity

V Kumbhar, R Raskar, R Chafle, V Nikam… - Results in …, 2023 - Elsevier
A simple, mild, and efficient protocol has been developed for the synthesis of 3, 3′-bis
(indolyl) methanes (BIMs) using prolinium hydrogen sulfate (ProHSO 4) as a catalyst under …

Synthesis of bis (indolyl) methanes using a catalytic amount of ZnO under solvent‐free conditions

M Hosseini‐Sarvari - Synthetic Communications, 2008 - Taylor & Francis
Efficient electrophilic substitution reactions of indoles with various aromatic aldehydes were
carried out using a catalytic amount of ZnO under solvent‐free conditions to afford the …