Mammalian spermatogenesis requires a stem cell pool, a period of amplification of cell
numbers, the completion of reduction division to haploid cells (meiosis), and the …

Spermatogenesis is a complex differentiation process coordinated spatiotemporally across
and along seminiferous tubules. Cellular heterogeneity has made it challenging to obtain …

Females of many species mate with multiple males, thereby inciting competition among
ejaculates from rival males for fertilization. In response to increasing sperm competition …

The determination of the chimpanzee genome sequence provides a means to study both
structural and functional aspects of the evolution of the human genome. Here we compare …

The testes produce the male gametes and the male sexual hormones (androgens). The term
spermatogenesis describes and includes all the processes involved in the production of …

This review looks into the phylogeny of spermatogonial stem cells and describes their basic
biological features. We are focusing on species-specific differences of spermatogonial stem …

Cholesterol provided by low-or high-density lipoprotein is the precursor for biosynthesis of
progesterone. Once inside the cell, cholesterol can be used for steroidogenesis or esterified …

To date, in the human seminiferous epithelium, only six associations of cell types have been
distinguished, subdividing the epithelial cycle into six stages of very different duration. This …

The human spermatogonial compartment is essential for daily production of millions of
sperm. Despite this crucial role, the molecular signature, kinetic behavior and regulation of …

Genes involved in spermatogenesis tend to evolve rapidly, but we lack a clear
understanding of how protein sequences and patterns of gene expression evolve across this …