T helper type (Th1/Th2) responses to SARS-CoV-2 and influenza A (H1N1) virus: From cytokines produced to immune responses

E Aleebrahim-Dehkordi, B Molavi, M Mokhtari… - Transplant …, 2022 - Elsevier
Cytokines produced by T helper cells (T h cells) have essential roles in the body's defense
against viruses. Type 1 T helper (Th1) cells are essential for the host defense toward …

The role of interleukin 6 during viral infections

L Velazquez-Salinas, A Verdugo-Rodriguez… - Frontiers in …, 2019 - frontiersin.org
Our recently published research on the characterization of vesicular stomatitis virus (VSV)
pathogenesis in swine, identified a systemic upregulation of interleukin 6 (IL-6) during the …

[HTML][HTML] Crimean–Congo hemorrhagic fever virus: progress in vaccine development

A Ozdarendeli - Diagnostics, 2023 - mdpi.com
Crimean–Congo hemorrhagic fever virus (CCHFV), a member of the Nairoviridae family and
Bunyavirales order, is transmitted to humans via tick bites or contact with the blood of …

A cynomolgus macaque model for Crimean–Congo haemorrhagic fever

E Haddock, F Feldmann, DW Hawman, M Zivcec… - Nature …, 2018 - nature.com
Crimean–Congo haemorrhagic fever (CCHF) is the most medically significant tick-borne
disease, being widespread in the Middle East, Asia, Africa and parts of Europe. Increasing …

Immunobiology of Crimean-Congo hemorrhagic fever

SE Rodriguez, DW Hawman, TE Sorvillo, TJ O'Neal… - Antiviral research, 2022 - Elsevier
Abstract Human infection with Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-
borne pathogen in the family Nairoviridae, can result in a spectrum of outcomes, ranging …

Recent advances in treatment Crimean–Congo hemorrhagic fever virus: A concise overview

O Gholizadeh, MM Jafari, R Zoobinparan… - Microbial …, 2022 - Elsevier
Abstract The Crimean Congo Hemorrhagic Fever Virus (CCHFV) is widespread in Africa,
Asia, and Europe, among other places. The disease was initially discovered in the Crimean …

[HTML][HTML] Animal models for Crimean-Congo hemorrhagic fever human disease

AR Garrison, DR Smith, JW Golden - Viruses, 2019 - mdpi.com
Crimean-Congo hemorrhagic fever virus (CCHFV) is an important tick-borne human
pathogen endemic throughout Asia, Africa and Europe. CCHFV is also an emerging virus …

Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus

TE Sorvillo, E Karaaslan, FEM Scholte, SR Welch… - npj Vaccines, 2024 - nature.com
Crimean-Congo hemorrhagic fever virus (CCHFV) can cause severe human disease and is
considered a WHO priority pathogen due to the lack of efficacious vaccines and antivirals. A …

Favipiravir and Ribavirin protect immunocompetent mice from lethal CCHFV infection

T Tipih, K Meade-White, D Rao, T Bushmaker, M Lewis… - Antiviral Research, 2023 - Elsevier
Crimean-Congo hemorrhagic fever virus (CCHFV) causes Crimean-Congo hemorrhagic
fever (CCHF) in humans with high morbidity and mortality. Currently, there is neither an …

Ribavirin for treating Crimean Congo haemorrhagic fever

S Johnson, N Henschke, N Maayan… - Cochrane Database …, 2018 - cochranelibrary.com
Background Crimean Congo haemorrhagic fever (CCHF) is a tick‐borne disease that occurs
in parts of Asia, Europe and Africa. Since 2000 the infection has caused epidemics in …