The unique architecture of the mammalian lung is required for adaptation to air breathing at
birth and thereafter. Understanding the cellular and molecular mechanisms controlling its …

Tenascin-C is an extracellular matrix glycoprotein that is specifically and transiently
expressed upon tissue injury. Upon tissue damage, tenascin-C plays a multitude of different …

Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very
restricted pattern of expression but an enormously diverse range of functions. Here, we …

In this review, we discuss the structure and function of the extracellular matrix protein family
of tenascins with emphasis on their involvement in human pathologies. The article is divided …

Background Previous studies have related vitamin D supplementation to a lower risk of
acute respiratory tract infection. Emerging evidence suggests that vitamin D insufficiency is …

Clinical pulmonary hypertension is characterized by a sustained elevation in pulmonary
arterial pressure. Pulmonary vascular remodeling involves structural changes in the normal …

An increasing volume of experimental data indicates that the adventitial fibroblast, in both
the pulmonary and systemic circulations, is a critical regulator of vascular wall function in …

Tenascins are a family of extracellular matrix proteins that evolved in early chordates. There
are four family members: tenascin-X, tenascin-R, tenascin-W, and tenascin-C. Tenascin-X …

Although fibroblasts are dormant in normal tissue, they exhibit explosive activation during
wound healing and perpetual activation in pathologic fibrosis and cancer stroma. The key …

Fibroblast heterogeneity has been shown within the unwounded mouse dorsal dermis, with
fibroblast subpopulations being identified according to anatomical location and embryonic …