The anti-asthmatic potential of flavonol kaempferol in an experimental model of allergic airway inflammation

M Molitorisova, M Sutovska, I Kazimierova… - European Journal of …, 2021 - Elsevier
Flavonol kaempferol possesses a broad spectrum of potent pharmacological activities that
seem to be effective in the modulation of allergic respiratory diseases. In our study, an …

Extracellular polysaccharide produced by Chlorella vulgaris–chemical characterization and anti-asthmatic profile

J Barboríková, M Šutovská, I Kazimierová… - International journal of …, 2019 - Elsevier
Microalgae are the lowest plant organisms producing a wide range of metabolites that make
them interesting organisms for industrial applications. Cultivation of green microalgal …

Quantitative In Vivo Characterization of Intracellular and Extracellular pH Profiles in Heterogeneous Tumors: A Novel Method Enabling Multiparametric pH Analysis

NW Lutz, Y Le Fur, J Chiche, J Pouysségur… - Cancer research, 2013 - AACR
Acid production and transport are currently being studied to identify new targets for efficient
cancer treatment, as subpopulations of tumor cells frequently escape conventional therapy …

Echinacea complex–chemical view and anti-asthmatic profile

M Šutovská, P Capek, I Kazimierová, L Pappová… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Echinacea purpurea (L.) Moench is one of the mostly used
herbs in the traditional medicine for the treatment of respiratory diseases. Modern interest in …

Segmentation of motion regions for biomechanical systems

D Koniar, L Hargaš, S Štofan - Procedia Engineering, 2012 - Elsevier
This paper focuses on main principles of high speed imaging used for motion analysis of
microscopic biomechanical objects represented by cilia of respiratory apparatus epithelium …

Pharmacodynamic evaluation of RP3128, a novel and potent CRAC channel inhibitor in guinea pig models of allergic asthma

M Sutovska, M Kocmalova, S Franova… - European Journal of …, 2016 - Elsevier
The increase in intracellular Ca 2+ levels through the activation of Ca 2+ release-activated
Ca 2+(CRAC) channels is essential for mediating a wide scale of immune cell responses …

[HTML][HTML] Negative impact of anesthesia with midazolam, sufentanil, and propofol used in pediatric flexible bronchoscopy on the tracheal ciliary beat frequency in …

M Joskova, P Durdik, M Sutovska, M Grendar… - Journal of …, 2020 - Elsevier
There is no direct evidence for the exact cilia-inhibitory effects of opioids, which are
generally used to achieve general anesthesia in combination with other anesthetic drugs …

Effects of inhalation of STIM-orai antagonist SKF 96365 on ovalbumin-induced airway remodeling in Guinea pigs

M Šutovská, M Kocmálová, I Kazimierová… - Best Practice in Health …, 2021 - Springer
Airway remodeling (AR) consists of wall thickening and hyperreactivity. STIM (stromal
interaction molecule) and Orai protein pathways mediate extracellular Ca2+ signals …

The effect of erdosteine on airway defence mechanisms and inflammatory cytokines in the settings of allergic inflammation

S Fraňová, I Kazimierová, L Pappová… - Pulmonary …, 2019 - Elsevier
Introduction Mucoactive agent, erdosteine, besides mucolytic activity, is characterized by
many other pharmacodynamic properties which could be beneficial in the management of …

Sensenbrenner syndrome presenting with severe anorexia, failure to thrive, chronic kidney disease and angel-shaped middle phalanges in two siblings

M Brndiarova, M Mraz, Z Kolkova, F Cisarik… - Molecular …, 2021 - karger.com
Sensenbrenner syndrome is a very rare autosomal recessive disorder caused by variants in
genes involved in the functional development of primary cilia. Typical clinical manifestations …