Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Abstract Growth hormone (GH), insulin-like growth factor (IGF)-I and insulin have potent
growth-promoting and anabolic actions. Their potential involvement in tumor promotion and …

MicroRNAs (miRNAs) are single-stranded, noncoding RNAs that are important in many
biological processes,. Although the oncogenic and tumour-suppressive functions of several …

Human growth hormone (GH) is a classical pituitary endocrine hormone that is essential for
normal postnatal growth and has pleiotropic effects across multiple physiological systems …

Since its discovery nearly a century ago, over 100,000 studies of growth hormone (GH) have
investigated its structure, how it interacts with the GH receptor and its multiple actions. These …

It is now apparent that regulation of blood vessel growth contributes to the classical actions
of hormones on development, growth, and reproduction. Endothelial cells are ideally …

Emerging evidence indicates that the miR-23a/24-2/27a cluster may possess a causal role
in mammary tumorigenesis and function as a novel class of oncogenes. However, the …

The potentially different genetics and epigenetics in the primary tumors and metastases
affect the efficacy of treatment in breast cancer patients. Nevertheless, the cellular and …

Breast cancer is the most common malignancy in women in the United States but significant
disparities exist for African American women compared to Caucasian women. African …

Plakoglobin (also known as?-catenin) is a member of the Armadillo family of proteins and a
paralog of β-catenin. Plakoglobin is a component of both the adherens junctions and …