Neurofilament proteins have been validated as specific body fluid biomarkers of neuro-
axonal injury. The advent of highly sensitive analytical platforms that enable reliable …

The recent introduction of new-generation immunoassay methods allows the reliable
quantification of structural brain markers in peripheral matrices. Neurofilament light chain …

Background Cognitive deficits are among the main disabling symptoms in COVID-19
patients and post-COVID syndrome (PCS). Within brain regions, the hippocampus, a key …

Background Previous population-based, longitudinal studies have shown that delirium is
associated with an increased risk of dementia and cognitive decline. However, the …

Background Neurological conditions represent an important driver of paediatric disability
burden worldwide. Measurement of serum neurofilament light chain (sNfL) concentrations, a …

Background and aims To investigate the prognostic value of blood neurofilament light chain
protein (NfL) levels in the acute phase of coronavirus disease 2019 (COVID-19). Methods …

Sepsis is the most common cause of admission to intensive care units worldwide. Sepsis
patients frequently suffer from sepsis-associated encephalopathy (SAE) reflecting acute …

Neurofilament light chain is an established marker of neuroaxonal injury that is elevated in
CSF and blood across various neurological diseases. It is increasingly used in clinical …

Concomitant Alzheimer's disease (AD) pathology is a frequent event in the context of Lewy
body disease (LBD), occurring in approximately half of all cases. Evidence shows that LBD …

Background and Objectives Patients with Lewy body disease (LBD) often show a co-
occurring Alzheimer disease (AD) pathology. CSF biomarkers allow the detection in vivo of …