Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …

The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a
protein, but this does not mean that such RNAs do not contain information nor have function …

Methylation of the N 6 position of adenosine (m 6 A) is a posttranscriptional modification of
RNA with poorly understood prevalence and physiological relevance. The recent discovery …

We used cross-linking and immunoprecipitation coupled with high-throughput sequencing to
identify binding sites in 6,304 genes as the brain RNA targets for TDP-43, an RNA binding …

Recent transcriptome studies have revealed that a large number of transcripts in mammals
and other organisms do not encode proteins but function as noncoding RNAs (ncRNAs) …

In the past century, nearly all of the biological sciences have been directly affected by
discoveries and developments in genetics, a fast-evolving subject with important theoretical …

Long non-coding RNAs (lncRNAs), which represent a new frontier in molecular biology, play
important roles in regulating gene expression at epigenetic, transcriptional and post …

Although accumulating evidence has provided insight into the various functions of long-non-
coding RNAs (lncRNAs), the exact functions of the majority of such transcripts are still …

Recently, a non-coding RNA expressed from a human pseudogene was reported to regulate
the corresponding protein-coding mRNA by acting as a decoy for microRNAs (miRNAs) that …

Long transcripts that do not encode protein have only rarely been the subject of
experimental scrutiny. Presumably, this is owing to the current lack of evidence of their …