Myocardial fibrosis, the expansion of the cardiac interstitium through deposition of
extracellular matrix proteins, is a common pathophysiologic companion of many different …

Cardiac fibrosis describes the inappropriate proliferation of cardiac fibroblasts (CFs), leading
to accumulation of extracellular matrix (ECM) proteins in the cardiac muscle, which is found …

Fibrosis, a common process of chronic inflammatory diseases, is defined as a repair
response disorder when organs undergo continuous damage, ultimately leading to scar …

The collagen family contains 28 proteins, predominantly expressed in the extracellular
matrix (ECM) and characterized by a triple-helix structure. Collagens undergo several …

Cardiac fibrosis is a common pathological consequence of most myocardial diseases. It is
associated with the excessive accumulation of extracellular matrix proteins as well as …

Cell death constitutes a critical component of the pathophysiology of cardiovascular
diseases. A growing array of non-apoptotic forms of regulated cell death (RCD)—such as …

Myocardial fibrosis (MF) is a reactive remodeling process in response to myocardial injury. It
is mainly manifested by the proliferation of cardiac muscle fibroblasts and secreting …

Cardiac fibroblasts play a key role in the process of myocardial remodeling and myocardial
fibrosis, which will eventually lead to heart failure. Quercetin Dihydrate has been studied in …

Hypertension or angiotensin II (Ang II) induces cardiac inflammation and fibrosis, thus
contributing to cardiac remodeling. MicroRNAs (miRNAs) are considered crucial regulators …

Myocardial fibroblasts play a crucial role in heart structure and function. In recent years,
significant progress has been made in understanding the epigenetic regulation of …