Chondrogenesis of dedifferentiated chondrocytes and mesenchymal stem cells is influenced
not only by soluble molecules like growth factors, but also by the cell environment itself. The …

Damage to the articular cartilage is an important, prevalent, and unsolved clinical issue for
the orthopaedic surgeon. This review summarizes innovative basic research approaches …

Background MSCs isolated from bone marrow (BM-MSCs) have well-established
chondrogenic potential, but MSCs derived from the synovial membrane (SM-MSCs) and …

Aim The aim of this work was the development of successful cell therapy techniques for
cartilage engineering. This will depend on the ability to monitor non-invasively transplanted …

Articular cartilage has limited capacity for natural regeneration and repair. In the present
study, we evaluated kartogenin (KGN), a bioactive small heterocyclic molecule, for its effect …

We examined the respective influence of a sequential or a continuous hypoxia during
expansion and transforming growth factor beta 1-driven chondrogenic differentiation of …

A bipotential polyelectrolyte complex with biphasic calcium phosphate (BCP) powder
dispersion provides an excellent option for protein adsorption and cell attachment and can …

Cartilage tissue engineering is making progress, but the competing available strategies still
leave room for improvement and consensual overviews regarding the best combinations of …

Introduction: Osteoarthritis (OA) is the most common chronic musculoskeletal disorder.
Nowadays, the role of synovial fluid mesenchymal stem cells (SF MSCs) is increasingly …

Tissue engineering is being explored as a suitable strategy to repair tissues that have no
capability of regenerating by themselves, such as articular hyaline cartilage in the knee. This …