Brain aging mechanisms with mechanical manifestations
Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
Cerebral small vessel disease pathology in COVID-19 patients: A systematic review
Cerebral small vessel disease (CSVD) is the leading cause of vascular cognitive impairment
and is associated with COVID-19. However, contributing factors that often accompany CSVD …
and is associated with COVID-19. However, contributing factors that often accompany CSVD …
White matter hyperintensity topography in Alzheimer's disease and links to cognition
Introduction White matter hyperintensities (WMH) are often described in Alzheimer's disease
(AD), but their topography and specific relationships with cognition remain unclear. Methods …
(AD), but their topography and specific relationships with cognition remain unclear. Methods …
Association of data-driven white matter hyperintensity spatial signatures with distinct cerebral small vessel disease etiologies
CL Phuah, Y Chen, JF Strain, N Yechoor… - Neurology, 2022 - AAN Enterprises
Background and Objectives Topographical distribution of white matter hyperintensities
(WMH) are hypothesized to vary by cerebrovascular risk factors. We used an unbiased …
(WMH) are hypothesized to vary by cerebrovascular risk factors. We used an unbiased …
Visceral obesity relates to deep white matter hyperintensities via inflammation
Objective White matter hyperintensities (WMHs) are linked to vascular risk factors and
increase the risk of cognitive decline, dementia, and stroke. We here aimed to determine …
increase the risk of cognitive decline, dementia, and stroke. We here aimed to determine …
Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging
The concept of brain maintenance refers to the preservation of brain integrity in older age,
while cognitive reserve refers to the capacity to maintain cognition in the presence of …
while cognitive reserve refers to the capacity to maintain cognition in the presence of …
Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities
Background and Purpose: Periventricular white matter hyperintensities (WMH; PVWMH) and
deep WMH (DWMH) are regional classifications of WMH and reflect proposed differences in …
deep WMH (DWMH) are regional classifications of WMH and reflect proposed differences in …
Associations between white matter hyperintensity burden, cerebral blood flow and transit time in small vessel disease: an updated meta-analysis
Cerebral small vessel disease (SVD) is a major contributor to stroke and dementia,
characterized by white matter hyperintensities (WMH) on neuroimaging. WMH are …
characterized by white matter hyperintensities (WMH) on neuroimaging. WMH are …
Modifiable and non-modifiable risk factors of dementia on midlife cerebral small vessel disease in cognitively healthy middle-aged adults: the PREVENT-Dementia …
Background Considerable overlap exists between the risk factors of dementia and cerebral
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …
small vessel disease (SVD). However, studies remain limited to older cohorts wherein …
Spatial patterns of white matter hyperintensities: a systematic review
Background White matter hyperintensities are an important marker of cerebral small vessel
disease. This disease burden is commonly described as hyperintense areas in the cerebral …
disease. This disease burden is commonly described as hyperintense areas in the cerebral …