Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by
the American Heart Association in response to the high prevalence of metabolic and kidney …

ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Interval training is a simple concept that refers to repeated bouts of relatively hard work
interspersed with recovery periods of easier work or rest. The method has been used by …

Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

Background: Open Access Editor's Choice Review Obesity and Cardiometabolic Risk
Factors: From Childhood to Adulthood by Dorota Drozdz 1,*,†, Julio Alvarez-Pitti 2, 3, 4,† …

Objectives To compare hospitalisation rates, intensive care unit (ICU) admissions and
mortality for patients with COVID-19 who were consistently inactive, doing some activity or …

Objective To examine and summarise evidence from meta-analyses of cohort studies that
evaluated the predictive associations between baseline cardiorespiratory fitness (CRF) and …

Childhood obesity is, according to the WHO, one of the most serious challenges of the 21st
century. More than 100 million children have obesity today. Already during childhood …

This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …