Bone and mineral disorders in chronic kidney disease: implications for cardiovascular health and ageing in the general population

A Covic, M Vervloet, ZA Massy, PU Torres… - The lancet Diabetes & …, 2018 - thelancet.com
The patient with chronic kidney disease (CKD) represents an extreme model for
arteriosclerosis, vascular calcification, and bone disorders, all of which are also associated …

Standardizing compression testing for measuring the stiffness of human bone

S Zhao, M Arnold, S Ma, RL Abel, JP Cobb… - Bone & joint …, 2018 - boneandjoint.org.uk
Objectives The ability to determine human bone stiffness is of clinical relevance in many
fields, including bone quality assessment and orthopaedic prosthesis design. Stiffness can …

[BOOK][B] Microcomputed tomography: methodology and applications

SR Stock - 2019 - taylorfrancis.com
MicroComputed Tomography has become the gold standard for studying 3D microscopic
structures nondestructively, and this book provides up-to-date coverage of the modality. The …

Human mesenchymal stem cells differentiate into an osteogenic lineage in presence of strontium containing bioactive glass nanoparticles

P Naruphontjirakul, O Tsigkou, S Li, AE Porter… - Acta biomaterialia, 2019 - Elsevier
While bioactive glass and ions released during its dissolution are known to stimulate
osteoblast cells, the effect bioactive glass has on human stem cells is not clear. Here, we …

Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis: EMAS position statement

P Anagnostis, SA Paschou, G Mintziori, I Ceausu… - Maturitas, 2017 - Elsevier
Background Bisphosphonates and denosumab are used extensively in the treatment of
postmenopausal osteoporosis. Despite their proven efficacy in the reduction of vertebral and …

[HTML][HTML] Crosstalk between skeletal and neural tissues is critical for skeletal health

N Abeynayake, A Arthur, S Gronthos - Bone, 2021 - Elsevier
Emerging evidence in the literature describes a physical and functional association between
the neural and skeletal systems that forms a neuro-osteogenic network. This communication …

An integrated experimental-computational framework to assess the influence of microstructure and material properties on fracture toughness in clinical specimens of …

A Demirtas, EA Taylor, B Gludovatz, RO Ritchie… - Journal of the …, 2023 - Elsevier
Microstructural and compositional changes that occur due to aging, pathological conditions,
or pharmacological treatments alter cortical bone fracture resistance. However, the relative …

Osteoporosis, bone mineral density and CKD–MBD: treatment considerations

J Bover, L Bailone, V López-Báez, S Benito… - Journal of …, 2017 - Springer
Osteoporosis and chronic kidney disease (CKD) have both independently important
potential impact on bone health. A significant number of patients with CKD stages 3a–5D …

High-affinity extended bisphosphonate-based coordination polymers as promising candidates for bone-targeted drug delivery

L Carmona-Sarabia, G Quiñones Vélez… - … Applied Materials & …, 2023 - ACS Publications
Extended bisphosphonate-based coordination polymers (BPCPs) were produced when 1,
1′-biphenyl-4, 4′-bisphosphonic acid (BPBPA), the analogue of 1, 1′-biphenyl-4, 4 …

Sacral insufficiency fractures: a review of risk factors, clinical presentation, and management

I Urits, V Orhurhu, J Callan, NV Maganty… - Current pain and …, 2020 - Springer
Abstract Purpose of the Review Sacral insufficiency fractures (SIF) are a common and often
underdiagnosed source of low back pain. In patients with SIF, there is both a compromised …