Genetics studies of autism spectrum disorder (ASD) have identified several risk genes that
are key regulators of synaptic plasticity. Indeed, many of the risk genes that have been …

Protein‐protein interaction plays key role in predicting the protein function of target protein
and drug ability of molecules. The majority of genes and proteins realize resulting …

Associations between modifiable exposures and disease seen in observational
epidemiology are sometimes confounded and thus misleading, despite our best efforts to …

Observational epidemiological studies suffer from many potential biases, from confounding
and from reverse causation, and this limits their ability to robustly identify causal …

Summary 1 The role of phenotypic plasticity in evolution has historically been a contentious
issue because of debate over whether plasticity shields genotypes from selection or …

Plasticity can allow organisms to maintain consistent performance across a wide range of
environmental conditions. However, it remains largely unknown how costly plasticity is and …

Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Neurons can produce action potentials with high temporal precision. A fundamental issue is
whether, and how, this capability is used in information processing. According to the 'cell …

Cryptic genetic variation (CGV) is invisible under normal conditions, but it can fuel evolution
when circumstances change. In theory, CGV can represent a massive cache of adaptive …

Most genetic research has used inbred organisms and has not explored the complexity of
natural genetic variation present in outbred populations. The translation of genotype to …