[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …
attention as a way to better mimic the complex interactions between individual cells and the …
Strategies to capitalize on cell spheroid therapeutic potential for tissue repair and disease modeling
Cell therapies offer a tailorable, personalized treatment for use in tissue engineering to
address defects arising from trauma, inefficient wound repair, or congenital malformation …
address defects arising from trauma, inefficient wound repair, or congenital malformation …
Engineered hydrogel microspheres for spheroids and organoids construction
T Gai, Y Zhang, G Li, F Zhou, C He, X Wang… - Chemical Engineering …, 2024 - Elsevier
Spheroids and organoids are cellular aggregates formed by multicellular culture under 3D
matrix microenvironment in vitro, capable of recapitulating partial structures, functions and …
matrix microenvironment in vitro, capable of recapitulating partial structures, functions and …
Applications of biomaterials in 3D cell culture and contributions of 3D cell culture to drug development and basic biomedical research
The process of evaluating the efficacy and toxicity of drugs is important in the production of
new drugs to treat diseases. Testing in humans is the most accurate method, but there are …
new drugs to treat diseases. Testing in humans is the most accurate method, but there are …
Composite Hydrogels in Three-Dimensional in vitro Models
3-dimensional (3D) in vitro models were developed in order to mimic the complexity of real
organ/tissue in a dish. They offer new possibilities to model biological processes in more …
organ/tissue in a dish. They offer new possibilities to model biological processes in more …
Regenerative cell therapy with 3D bioprinting
Regenerative medicine uses viable cells that are injected, grafted, or implanted into a
patient to exert a desired therapeutic effect, such as healing of traumatic wounds. However …
patient to exert a desired therapeutic effect, such as healing of traumatic wounds. However …
Automation, monitoring, and standardization of cell product manufacturing
MN Doulgkeroglou, A Di Nubila, B Niessing… - … in Bioengineering and …, 2020 - frontiersin.org
Although regenerative medicine products are at the forefront of scientific research,
technological innovation, and clinical translation, their reproducibility and large-scale …
technological innovation, and clinical translation, their reproducibility and large-scale …
4D self‐morphing culture substrate for modulating cell differentiation
As the most versatile and promising cell source, stem cells have been studied in
regenerative medicine for two decades. Currently available culturing techniques utilize a 2D …
regenerative medicine for two decades. Currently available culturing techniques utilize a 2D …
Accelerating cardiovascular research: recent advances in translational 2D and 3D heart models
In vitro modelling the complex (patho‐) physiological conditions of the heart is a major
challenge in cardiovascular research. In recent years, methods based on three‐dimensional …
challenge in cardiovascular research. In recent years, methods based on three‐dimensional …
Advanced biomedical applications based on emerging 3D cell culturing platforms
It is of great value to develop reliable in vitro models for cell biology and toxicology.
However, ethical issues and the decreasing number of donors restrict the further use of …
However, ethical issues and the decreasing number of donors restrict the further use of …