[HTML][HTML] Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration

A Atwal, TP Dale, M Snow, NR Forsyth… - Advances in colloid and …, 2023 - Elsevier
The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed
significant challenges for healthcare practitioners, researchers, and individuals suffering …

Intra-articular drug delivery for osteoarthritis treatment

Y Cao, Y Ma, Y Tao, W Lin, P Wang - Pharmaceutics, 2021 - mdpi.com
Osteoarthritis (OA) is the most prevalent degenerative joint disease affecting millions of
people worldwide. Currently, clinical nonsurgical treatments of OA are only limited to pain …

Chitosan/Pluronic F127 thermosensitive hydrogel as an injectable dexamethasone delivery carrier

J García-Couce, M Tomás, G Fuentes, I Que, A Almirall… - Gels, 2022 - mdpi.com
Intra-articular administration of anti-inflammatory drugs is a strategy that allows localized
action on damaged articular cartilage and reduces the side effects associated with systemic …

Stimulus‐Responsive Drug Delivery Nanoplatforms for Osteoarthritis Therapy

Q Jiang, S Zhang - Small, 2023 - Wiley Online Library
Osteoarthritis (OA) is one of the most prevalent age‐related degenerative diseases. With an
increasingly aging global population, greater numbers of OA patients are providing clear …

Advanced injectable hydrogels for cartilage tissue engineering

S Zhu, Y Li, Z He, L Ji, W Zhang, Y Tong… - … in bioengineering and …, 2022 - frontiersin.org
The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …

Engineering hyaluronic acid for the development of new treatment strategies for osteoarthritis

YS Kim, F Guilak - International journal of molecular sciences, 2022 - mdpi.com
Osteoarthritis (OA) is a degenerative joint disease that is characterized by inflammation of
the joints, degradation of cartilage, and the remodeling of other joint tissues. Due to the …

Applications and prospects of intra-articular drug delivery system in arthritis therapeutics

P Song, Z Cui, L Hu - Journal of Controlled Release, 2022 - Elsevier
Arthritis is a kind of chronic disease that affects joints and muscles with the symptoms of joint
pain, inflammation and limited movement of joints. Among various clinical therapies, drug …

Local drug delivery systems for inflammatory diseases: Status quo, challenges, and opportunities

YC Chen, SF Gad, D Chobisa, Y Li, Y Yeo - Journal of Controlled Release, 2021 - Elsevier
Inflammation that is not resolved in due course becomes a chronic disease. The treatment of
chronic inflammatory diseases involves a long-term use of anti-inflammatory drugs such as …

Recent developments and current applications of hydrogels in osteoarthritis

T Zhao, Z Wei, W Zhu, X Weng - Bioengineering, 2022 - mdpi.com
Osteoarthritis (OA) is a common degenerative joint disease that causes disability if left
untreated. The treatment of OA currently requires a proper delivery system that avoids the …

Regeneration of articular cartilage defects: Therapeutic strategies and perspectives

X Guo, L **, M Yu, Z Fan, W Wang… - Journal of Tissue …, 2023 - journals.sagepub.com
Articular cartilage (AC), a bone-to-bone protective device made of up to 80% water and
populated by only one cell type (ie chondrocyte), has limited capacity for regeneration and …