Electroporation (EP) is a commonly used strategy to increase cell permeability for
intracellular cargo delivery or irreversible cell membrane disruption using electric fields. In …

Innate cell function can be artificially engineered and reprogrammed by introducing
biomolecules, such as DNAs, RNAs, plasmid DNAs, proteins, or nanomaterials, into the …

The recent success of mRNA therapeutics against pathogenic infections has increased
interest in their use for other human diseases including cancer. However, the precise …

Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …

Electroporation is a fundamental technique for applications in biotechnology. To date, the
ongoing research on cell membrane electroporation has explored its mechanism, principles …

Herein, we studied localized electroporation and gene transfection of mammalian cells
using a metallodielectric hybrid micromotor that is magnetically and electrically powered …

Localized micro/nano-electroporation (MEP/NEP) shows tremendous potential in cell
transfection with high cell viability, precise dose control, and good transfection efficacy. In …

Recently, gene therapy has become a subject of considerable research and has been
widely evaluated in various disease models. Though it is considered as a stand-alone agent …

Gene electrotransfer (GET) is a widely used method for nucleic acids' delivery into cells. We
explored, evaluated, and demonstrated the potential use of different pulse durations for …

Temperature is a critical—yet sometimes overlooked—parameter in microfluidics.
Microfluidic devices can experience heating inside their channels during operation due to …