Careful selection of photocaging approaches is critical to achieve fast and well synchronized
reaction initiation and perform successful time-resolved structural biology experiments. This …

Water-soluble myo-inositol phosphates have long been characterized as second
messengers. The signaling properties of these compounds are determined by the number …

Technical challenges have to date prevented a complete profiling of the levels of myo-
inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) in mammalian tissues. Here, we …

Conspectus Much like linear, branched, and cyclic alkanes, condensed phosphates exist as
linear, branched, and cyclic structures. Inasmuch as alkanes are the cornerstone of organic …

Inositol pyrophosphates (PP-IPs) such as 5-diphosphoinositol pentakisphosphate (5-IP7)
are inositol metabolites containing high-energy phosphoanhydride bonds. Biosynthesis of …

Inositol pyrophosphates (PP-InsPs) are an important group of intracellular signaling
molecules. Derived from inositol phosphates (InsPs), these molecules feature the presence …

There has been a recent upsurge in the study and application of approaches utilizing
cyclotriphosphate 1 (cyclo‐TP, also known as trimetaphosphate, TMP) and/or proceeding …

The inositol pyrophosphates (PP-InsPs) are an important group of cellular messengers that
influence a broad range of biological processes. To elucidate the functions of these high …

Sodium/potassium-transporting adenosine triphosphatase (Na+/K+-ATPase) is one of the
most abundant cell membrane proteins and is essential for eukaryotes. Endogenous …

Nucleoside triphosphates (NTPs) are essential in various biological processes. Cellular or
even organismal controlled delivery of NTPs would be highly desirable, yet in cellulo and in …