Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Efficient separation of enantiomers using stereoregular chiral polymers

J Shen, Y Okamoto - Chemical reviews, 2016 - ACS Publications
Biosystems, including ourselves, are very sensitive to the chirality of compounds; for
instance, monosodium L-glutamate is tasty, while its D-isomer is tasteless, and in many …

Are highly stable covalent organic frameworks the key to universal chiral stationary phases for liquid and gas chromatographic separations?

C Yuan, W Jia, Z Yu, Y Li, M Zi… - Journal of the American …, 2022 - ACS Publications
High-performance liquid chromatography (HPLC) and gas chromatography (GC) over chiral
stationary phases (CSPs) represent the most popular and highly applicable technology in …

Chiral pharmaceuticals: A review on their environmental occurrence and fate processes

E Sanganyado, Z Lu, Q Fu, D Schlenk, J Gan - Water Research, 2017 - Elsevier
More than 50% of pharmaceuticals in current use are chiral compounds. Enantiomers of the
same pharmaceutical have identical physicochemical properties, but may exhibit differences …

Processes to separate enantiomers

H Lorenz, A Seidel‐Morgenstern - … Chemie International Edition, 2014 - Wiley Online Library
The provision of pure enantiomers is of increasing importance not only for the
pharmaceutical industry but also for agrochemistry and biotechnology. In general, there are …

Chiral recognition by enantioselective liquid chromatography: mechanisms and modern chiral stationary phases

M Lämmerhofer - Journal of Chromatography A, 2010 - Elsevier
An overview of the state-of-the-art in LC enantiomer separation is presented. This tutorial
review is mainly focused on mechanisms of chiral recognition and enantiomer distinction of …

Recent progress in the development of chiral stationary phases for high‐performance liquid chromatography

JH Zhang, SM **e, LM Yuan - Journal of separation science, 2022 - Wiley Online Library
Separations and analyses of chiral compounds are important in many fields, including
pharmaceutical production, preparation of chemical intermediates, and biochemistry. High …

Separation of enantiomers: needs, challenges, perspectives

NM Maier, P Franco, W Lindner - Journal of Chromatography A, 2001 - Elsevier
Chiral drugs, agrochemicals, food additives and fragrances represent classes of compounds
with high economic and scientific potential. First the present implications of their chiral …

Chiral stationary phases for liquid chromatography: recent developments

J Teixeira, ME Tiritan, MMM Pinto, C Fernandes - Molecules, 2019 - mdpi.com
The planning and development of new chiral stationary phases (CSPs) for liquid
chromatography (LC) are considered as continuous and evolutionary issues since the …

Chiral HPLC for efficient resolution of enantiomers

Y Okamoto, T Ikai - Chemical Society Reviews, 2008 - pubs.rsc.org
Resolution of racemic compounds is one of the potential ways of obtaining both
enantiomers. Among several resolution techniques in the past few decades, direct …