Injectable thermosensitive hydrogels are free-flowing polymer solutions at low or room
temperature, making them easy to encapsulate the therapeutic payload or cells via simply …

Thermoresponsive supramolecular assemblies have been extensively explored in diverse
formats, from injectable hydrogels to nanoscale carriers, for a variety of applications …

Some amphiphilic block copolymers exhibit sol–gel transition in water upon heating, which
affords a promising injectable thermogel in clinic and an interesting soft matter system. While …

The sustained release of both the hydrophilic drug and hydrophobic drug from one delivery
system remains challenging in pharmaceutics and biomaterials science. The combination of …

Degradability of biomaterials brings many opportunities as well as great challenges to their
clinical applications. However, reports of systematic in vivo biodegradation are rather limited …

Gemcitabine (Gem), an analogue of deoxycytidine, has potent antitumor activities against
various solid tumors and is an excellent radiosensitizer as well. However, Gem has a very …

It is very challenging to visualize implantable medical devices made of biodegradable
polymers in deep tissues. Herein, we designed a novel macromolecular contrast agent with …

It is a great challenge to prepare “functional artificial bone” for the repair of large segmental
defect, especially in weight-bearing bones. In this study, bioactive HA/PCL composite …

Diabetes and its complications have become a global challenge of public health. Herein, we
aimed to develop a long-acting delivery system of lixisenatide (Lixi), a glucose-dependent …

Biocompatible and biodegradable block copolymers composed of poly (ethylene
glycol)(PEG) and aliphatic polyester are a class of promising biomaterials. Herein, a …