The role of epigenetic change in autism spectrum disorders

YJ Loke, AJ Hannan, JM Craig - Frontiers in neurology, 2015 - frontiersin.org
Autism spectrum disorders (ASD) are a heterogeneous group of neurodevelopmental
disorders characterized by problems with social communication, social interaction, and …

Genetic and epigenetic etiology underlying autism spectrum disorder

SH Yoon, J Choi, WJ Lee, JT Do - Journal of clinical medicine, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized
by difficulties in social interaction, language development delays, repeated body …

Whole-genome sequencing of quartet families with autism spectrum disorder

RKC Yuen, B Thiruvahindrapuram, D Merico… - Nature medicine, 2015 - nature.com
Autism spectrum disorder (ASD) is genetically heterogeneous, with evidence for hundreds of
susceptibility loci. Previous microarray and exome-sequencing studies have examined …

MicroRNAs: key regulators in the central nervous system and their implication in neurological diseases

DD Cao, L Li, WY Chan - International journal of molecular sciences, 2016 - mdpi.com
MicroRNAs (miRNAs) are a class of small, well-conserved noncoding RNAs that regulate
gene expression post-transcriptionally. They have been demonstrated to regulate a lot of …

The involvement of Reelin in neurodevelopmental disorders

TD Folsom, SH Fatemi - Neuropharmacology, 2013 - Elsevier
Reelin is a glycoprotein that serves important roles both during development (regulation of
neuronal migration and brain lamination) and in adulthood (maintenance of synaptic …

Serum microRNA profiles in children with autism

M Mundalil Vasu, A Anitha, I Thanseem, K Suzuki… - Molecular autism, 2014 - Springer
Background As regulators of gene expression, microRNAs (miRNAs) play a key role in the
transcriptional networks of the develo** human brain. Circulating miRNAs in the serum …

[HTML][HTML] MicroRNA and posttranscriptional dysregulation in psychiatry

M Geaghan, MJ Cairns - Biological psychiatry, 2015 - Elsevier
Psychiatric syndromes, including schizophrenia, mood disorders, and autism spectrum
disorders, are characterized by a complex range of symptoms, including psychosis …

An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy

MJ Millan - Neuropharmacology, 2013 - Elsevier
Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

Aberrant expression of long noncoding RNAs in autistic brain

MN Ziats, OM Rennert - Journal of molecular neuroscience, 2013 - Springer
The autism spectrum disorders (ASD) have a significant hereditary component, but the
implicated genetic loci are heterogeneous and complex. Consequently, there is a gap in …

Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspring

FCR Zucchi, Y Yao, ID Ward, Y Ilnytskyy, DM Olson… - PloS one, 2013 - journals.plos.org
The gestational state is a period of particular vulnerability to diseases that affect maternal
and fetal health. Stress during gestation may represent a powerful influence on maternal …