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Utilizing graph machine learning within drug discovery and development
Graph machine learning (GML) is receiving growing interest within the pharmaceutical and
biotechnology industries for its ability to model biomolecular structures, the functional …
biotechnology industries for its ability to model biomolecular structures, the functional …
Language models enable zero-shot prediction of the effects of mutations on protein function
Modeling the effect of sequence variation on function is a fundamental problem for
understanding and designing proteins. Since evolution encodes information about function …
understanding and designing proteins. Since evolution encodes information about function …
Prottrans: Toward understanding the language of life through self-supervised learning
Computational biology and bioinformatics provide vast data gold-mines from protein
sequences, ideal for Language Models (LMs) taken from Natural Language Processing …
sequences, ideal for Language Models (LMs) taken from Natural Language Processing …
Long range arena: A benchmark for efficient transformers
Transformers do not scale very well to long sequence lengths largely because of quadratic
self-attention complexity. In the recent months, a wide spectrum of efficient, fast Transformers …
self-attention complexity. In the recent months, a wide spectrum of efficient, fast Transformers …
Generative pretraining from pixels
Inspired by progress in unsupervised representation learning for natural language, we
examine whether similar models can learn useful representations for images. We train a …
examine whether similar models can learn useful representations for images. We train a …
MSA transformer
Unsupervised protein language models trained across millions of diverse sequences learn
structure and function of proteins. Protein language models studied to date have been …
structure and function of proteins. Protein language models studied to date have been …
Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences
In the field of artificial intelligence, a combination of scale in data and model capacity
enabled by unsupervised learning has led to major advances in representation learning and …
enabled by unsupervised learning has led to major advances in representation learning and …
Bertology meets biology: Interpreting attention in protein language models
Transformer architectures have proven to learn useful representations for protein
classification and generation tasks. However, these representations present challenges in …
classification and generation tasks. However, these representations present challenges in …
Progen: Language modeling for protein generation
Generative modeling for protein engineering is key to solving fundamental problems in
synthetic biology, medicine, and material science. We pose protein engineering as an …
synthetic biology, medicine, and material science. We pose protein engineering as an …
Using deep learning to annotate the protein universe
Understanding the relationship between amino acid sequence and protein function is a long-
standing challenge with far-reaching scientific and translational implications. State-of-the-art …
standing challenge with far-reaching scientific and translational implications. State-of-the-art …