Designing microbial cell factories for the production of chemicals

JS Cho, GB Kim, H Eun, CW Moon, SY Lee - Jacs Au, 2022 - ACS Publications
The sustainable production of chemicals from renewable, nonedible biomass has emerged
as an essential alternative to address pressing environmental issues arising from our heavy …

[HTML][HTML] Dynamic control in metabolic engineering: Theories, tools, and applications

CJ Hartline, AC Schmitz, Y Han, F Zhang - Metabolic engineering, 2021 - Elsevier
Metabolic engineering has allowed the production of a diverse number of valuable
chemicals using microbial organisms. Many biological challenges for improving bio …

Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia pastoris

P Cai, X Duan, X Wu, L Gao, M Ye… - Nucleic Acids …, 2021 - academic.oup.com
The industrial yeast Pichia pastoris has been harnessed extensively for production of
proteins, and it is attracting attention as a chassis cell factory for production of chemicals …

Microbial adaptation to enhance stress tolerance

YS Tan, RK Zhang, ZH Liu, BZ Li, YJ Yuan - Frontiers in Microbiology, 2022 - frontiersin.org
Microbial cell factories have been widely used in the production of various chemicals.
Although synthetic biology is useful in improving the cell factories, adaptation is still widely …

Biosynthesis of catharanthine in engineered Pichia pastoris

J Gao, Y Zuo, F **
J Lian, C Schultz, M Cao, M HamediRad… - Nature …, 2019 - nature.com
Genome-scale engineering is an indispensable tool to understand genome functions due to
our limited knowledge of cellular networks. Unfortunately, most existing methods for genome …

Advances in the biosynthesis and metabolic engineering of rare ginsenosides

M Li, M Ma, Z Wu, X Liang, Q Zheng, D Li, T An… - Applied Microbiology …, 2023 - Springer
Rare ginsenosides are the deglycosylated secondary metabolic derivatives of major
ginsenosides, and they are more readily absorbed into the bloodstream and function as …