The kisspeptin-GnRH pathway in human reproductive health and disease
BACKGROUND The discovery of kisspeptin as key central regulator of GnRH secretion has
led to a new level of understanding of the neuroendocrine regulation of human reproduction …
led to a new level of understanding of the neuroendocrine regulation of human reproduction …
Kisspeptins and reproduction: physiological roles and regulatory mechanisms
Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …
have evolved to mediate the diverse internal and external environmental inputs that regulate …
Functional hypothalamic amenorrhea: an endocrine society clinical practice guideline
Abstract Cosponsoring Associations: The American Society for Reproductive Medicine, the
European Society of Endocrinology, and the Pediatric Endocrine Society. This guideline was …
European Society of Endocrinology, and the Pediatric Endocrine Society. This guideline was …
The endocrine manifestations of anorexia nervosa: mechanisms and management
Anorexia nervosa is a psychiatric disorder characterized by altered body image, persistent
food restriction and low body weight, and is associated with global endocrine dysregulation …
food restriction and low body weight, and is associated with global endocrine dysregulation …
Hypothalamic amenorrhea and the long-term health consequences
The menstrual cycle is a reproductive vital sign and provides insight into hormonal
imbalance as well as pregnancy. The significance of estrogen, however, extends beyond …
imbalance as well as pregnancy. The significance of estrogen, however, extends beyond …
[HTML][HTML] Physiology of GNRH and gonadotropin secretion
P Marques, K Skorupskaite, KS Rozario… - Endotext …, 2022 - ncbi.nlm.nih.gov
Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins, follicle …
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins, follicle …
[HTML][HTML] Stress, kisspeptin, and functional hypothalamic amenorrhea
B Meczekalski, O Niwczyk, G Bala, A Szeliga - Current Opinion in …, 2022 - Elsevier
Functional hypothalamic amenorrhea (FHA) is the most common cause of secondary
amenorrhea in women of reproductive age. FHA is predominantly caused by stress …
amenorrhea in women of reproductive age. FHA is predominantly caused by stress …
[PDF][PDF] Comprehensive review on kisspeptin and its role in reproductive disorders
Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is
known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of …
known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of …
Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders
BACKGROUND Kisspeptin is a key regulator of hypothalamic gonadotropin-releasing
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …
The relationship between gut and adipose hormones, and reproduction
BACKGROUND Reproductive function is tightly regulated by nutritional status. Indeed, it has
been well described that undernutrition or obesity can lead to subfertility or infertility in …
been well described that undernutrition or obesity can lead to subfertility or infertility in …