The importance of flavonoids and phytochemicals of medicinal plants with antiviral activities

MH Shahrajabian, W Sun… - Mini-Reviews in Organic …, 2022 - ingentaconnect.com
In this mini-review article, we have mentioned the key roles of some of the most important
herbal plants medicine containing flavonoids and phytochemicals with antiviral activities. All …

Recent progresses in the treatment of osteoporosis

SS Li, SH He, PY **e, W Li, XX Zhang, TF Li… - Frontiers in …, 2021 - frontiersin.org
Osteoporosis (OP) is a chronic bone disease characterized by aberrant microstructure and
macrostructure of bone, leading to reduced bone mass and increased risk of fragile …

Secreted frizzled related proteins in cardiovascular and metabolic diseases

H Guan, J Zhang, J Luan, H Xu, Z Huang… - Frontiers in …, 2021 - frontiersin.org
Abnormal gene expression and secreted protein levels are accompanied by extensive
pathological changes. Secreted frizzled related protein (SFRP) family members are …

Therapeutic potential of naturally occurring small molecules to target the wnt/β-catenin signaling pathway in colorectal cancer

LFS Oliveira, D Predes, HL Borges, JG Abreu - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is an emerging public health problem and the
second leading cause of death worldwide, with a significant socioeconomic impact in …

Targeting lncRNA/Wnt axis by flavonoids: A promising therapeutic approach for colorectal cancer

S Han, Y Cao, T Guo, Q Lin, F Luo - Phytotherapy Research, 2022 - Wiley Online Library
Despite the dramatic advances in our understanding of the etiology of colorectal cancer
(CRC) in recent decades, effective therapeutic strategies are still urgently needed …

Strategic outline of interventions targeting extracellular matrix for promoting healthy longevity

JYC Park, A King, V Björk, BW English… - … of Physiology-Cell …, 2023 - journals.physiology.org
The extracellular matrix (ECM), composed of interlinked proteins outside of cells, is an
important component of the human body that helps maintain tissue architecture and cellular …

Targeting Wnt/β-catenin pathway by flavonoids: implication for cancer therapeutics

P Pandey, F Khan, SA Seifeldin, K Alshaghdali… - Nutrients, 2023 - mdpi.com
The Wnt pathway has been recognized for its crucial role in human development and
homeostasis, but its dysregulation has also been linked to several disorders, including …

[HTML][HTML] Role of GSK-3β inhibitors: new promises and opportunities for Alzheimer's disease

SR Shri, S Manandhar, Y Nayak… - Advanced Pharmaceutical …, 2023 - ncbi.nlm.nih.gov
Abstract Glycogen synthase kinase-3 (GSK-3) was discovered to be a multifunctional
enzyme involved in a wide variety of biological processes, including early embryo formation …

[HTML][HTML] The synergistic treatment of cyclolinopeptide J and calcium carbonate nanoparticles for osteoporosis via BMP/Wnt signaling: In vivo and in vitro

J Chen, W Li, YY Lee, Z Cai, J Chen, Y Wang - Journal of Functional Foods, 2023 - Elsevier
This research focuses on the investigation of cyclolinopeptide J (CLJ), a bioactive peptide
naturally present in flaxseed, which loaded in porous calcium carbonate (CA) nanoparticles …

The potential therapeutic role of curcumin in osteoporosis treatment: based on multiple signaling pathways

K Wang - Frontiers in Pharmacology, 2024 - frontiersin.org
Osteoporosis is a common chronic metabolic bone disease caused by disturbances in
normal bone metabolism and an imbalance between osteoblasts and osteoclasts …