Ameloblastoma: current etiopathological concepts and management
Ameloblastoma is a benign odontogenic tumor of epithelial origin. It is locally aggressive
with unlimited growth capacity and has a high potential for malignant transformation as well …
with unlimited growth capacity and has a high potential for malignant transformation as well …
Odontogenic cysts and neoplasms
EA Bilodeau, BM Collins - Surgical pathology clinics, 2017 - Elsevier
This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The
clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and …
clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and …
Update from the 4th edition of the World Health Organization classification of head and neck tumours: odontogenic and maxillofacial bone tumors
JM Wright, M Vered - Head and neck pathology, 2017 - Springer
The 4th edition of the World Health Organization's Classification of Head and Neck Tumours
was published in January of 2017. This article provides a summary of the changes to …
was published in January of 2017. This article provides a summary of the changes to …
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma
Basal cell carcinoma (BCC) of the skin is the most common malignant neoplasm in humans.
BCC is primarily driven by the Sonic Hedgehog (Hh) pathway. However, its phenotypic …
BCC is primarily driven by the Sonic Hedgehog (Hh) pathway. However, its phenotypic …
Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma
Smoothened (SMO) inhibitors are under clinical investigation for the treatment of several
cancers. Vismodegib is approved for the treatment of locally advanced and metastatic basal …
cancers. Vismodegib is approved for the treatment of locally advanced and metastatic basal …
Ameloblastoma: a clinical review and trends in management
AC McClary, RB West, AC McClary, JR Pollack… - European Archives of …, 2016 - Springer
Ameloblastoma is a rare odontogenic neoplasm of the mandible and maxilla, with multiple
histologic variants, and high recurrence rates if improperly treated. The current mainstay of …
histologic variants, and high recurrence rates if improperly treated. The current mainstay of …
Activating FGFR2–RAS–BRAF Mutations in Ameloblastoma
NA Brown, D Rolland, JB McHugh, HC Weigelin… - Clinical Cancer …, 2014 - AACR
Purpose: Ameloblastoma is an odontogenic neoplasm whose overall mutational landscape
has not been well characterized. We sought to characterize pathogenic mutations in …
has not been well characterized. We sought to characterize pathogenic mutations in …
Odontogenic tumors: where are we in 2017?
JM Wright, MS Tekkeşin - Journal of Istanbul University Faculty of …, 2017 - dergipark.org.tr
Odontogenic tumors are a heterogeneous group of lesions of diverse clinical behavior and
histopathologic types, ranging from hamartomatous lesions to malignancy. Because …
histopathologic types, ranging from hamartomatous lesions to malignancy. Because …
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas
Hedgehog signaling mediates embryologic development of the central nervous system and
other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular …
other tissues and is frequently hijacked by neoplasia to facilitate uncontrolled cellular …
Phase II Study of Copanlisib in Patients With Tumors With PIK3CA Mutations: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1F
S Damodaran, F Zhao, DA Deming… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Activating mutations in PIK3CA are observed across multiple tumor types. The
NCI-MATCH (EAY131) is a tumor-agnostic platform trial that enrolls patients to targeted …
NCI-MATCH (EAY131) is a tumor-agnostic platform trial that enrolls patients to targeted …