Emerging and re-emerging coronaviruses in pigs

Q Wang, AN Vlasova, SP Kenney, LJ Saif - Current opinion in virology, 2019 - Elsevier
Highlights•Three coronaviruses are emerging/reemerging in pigs.•The three porcine
coronaviruses may have originated from other species.•The clinical signs and pathogenesis …

[HTML][HTML] Coronavirus genomic RNA packaging

PS Masters - Virology, 2019 - Elsevier
RNA viruses carry out selective packaging of their genomes in a variety of ways, many
involving a genomic packaging signal. The first coronavirus packaging signal was …

Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

AJ Brown, JJ Won, RL Graham, KH Dinnon III, AC Sims… - Antiviral research, 2019 - Elsevier
Abstract The genetically diverse Orthocoronavirinae (CoV) family is prone to cross species
transmission and disease emergence in both humans and livestock. Viruses similar to …

Broad receptor engagement of an emerging global coronavirus may potentiate its diverse cross-species transmissibility

W Li, RJG Hulswit, SP Kenney, I Widjaja, K Jung… - Proceedings of the …, 2018 - pnas.org
Porcine deltacoronavirus (PDCoV), identified in 2012, is a common enteropathogen of
swine with worldwide distribution. The source and evolutionary history of this virus is …

Trypsin treatment unlocks barrier for zoonotic bat coronavirus infection

VD Menachery, KH Dinnon III, BL Yount Jr… - Journal of …, 2020 - journals.asm.org
Traditionally, the emergence of coronaviruses (CoVs) has been attributed to a gain in
receptor binding in a new host. Our previous work with severe acute respiratory syndrome …

Coronaviruses

LJ Saif, Q Wang, AN Vlasova, K Jung… - Diseases of swine, 2019 - Wiley Online Library
Five swine coronaviruses (CoVs) have been identified: transmissible gastroenteritis virus
(TGEV) first described in 1946; porcine respiratory coronavirus (PRCV), a spike (S) gene …

Porcine deltacoronavirus infection and transmission in poultry, United States

PA Boley, MA Alhamo, G Lossie… - Emerging infectious …, 2020 - pmc.ncbi.nlm.nih.gov
Coronaviruses cause respiratory and gastrointestinal diseases in diverse host species.
Deltacoronaviruses (DCoVs) have been identified in various songbird species and in …

Porcine deltacoronavirus infection: Etiology, cell culture for virus isolation and propagation, molecular epidemiology and pathogenesis

K Jung, H Hu, LJ Saif - Virus research, 2016 - Elsevier
Abstract Porcine deltacoronavirus (PDCoV)(family Coronaviridae, genus Deltacoronavirus)
is a novel swine enteropathogenic coronavirus that causes acute diarrhea/vomiting …

Newly Emerged Porcine Deltacoronavirus Associated With Diarrhoea in Swine in China: Identification, Prevalence and Full‐Length Genome Sequence Analysis

D Song, X Zhou, Q Peng, Y Chen… - Transboundary and …, 2015 - Wiley Online Library
To identify and characterize aetiologic agent (s) associated with an outbreak of a severe
diarrhoea in piglets in Jiangxi, China, in March 2015, a nested reverse transcription …

Porcine deltacoronavirus: overview of infection dynamics, diagnostic methods, prevalence and genetic evolution

J Zhang - Virus research, 2016 - Elsevier
Porcine deltacoronavirus (PDCoV) was first reported in Hong Kong, China in 2012 and
reported in United States swine in February 2014. PDCoV has subsequently been detected …