It is almost ten years since the Banerjee 2009 report established that inappropriate
prescribing of antipsychotics in the elderly was occurring in the UK and such patients had an …

Sex or gender differences in the risk of Alzheimer's disease and related dementias (ADRD)
differ by world region, suggesting that there are potentially modifiable risk factors for …

Importance Chronic pain is common among the elderly and is associated with cognitive
deficits in cross-sectional studies; the population-level association between chronic pain …

Supraphysiologic-dose anabolic-androgenic steroid (AAS) use is associated with
physiologic, cognitive, and brain abnormalities similar to those found in people at risk for …

Background Emerging evidence suggests that comorbid posttraumatic stress disorder
(PTSD) and major depressive disorder (PTSD/MDD) may impose an even greater burden …

Dementia is a major concern among growing chronic diseases in the aging society and its
association with polypharmacy has not been adequately assessed. The objective of this …

Abstract Background The United States is currently facing an opioid crisis. Novel tools to
better comprehend dynamic molecular changes in the brain associated with the opioid …

Alzheimer's Disease (AD) is a neurodegenerative disorder that is still not fully understood.
Sex modifies AD vulnerability, but the reasons for this are largely unknown. We utilize two …

Objectives To determine whether higher cumulative proton pump inhibitor (PPI) exposure is
associated with greater dementia risk. Design Prospective population‐based cohort study …

Background Patients and their loved ones often report symptoms or complaints of cognitive
decline that clinicians note in free clinical text, but no structured screening or diagnostic data …