Incidences of altered development and neoplasia of male reproductive organs have
increased during the last 50 years, as shown by epidemiological data. These data are …

Discussions of the function of early nervous systems usually focus on a causal flow from
sensors to effectors, by which an animal coordinates its actions with exogenous changes in …

The sha** of a multicellular body, and the maintenance and repair of adult tissues require
fine-tuning of cell adhesion responses and the transmission of mechanical load between the …

Organ morphogenesis involves dynamic changes of tissue properties while cells adapt to
their mechanical environment through mechanosensitive pathways. How mechanical cues …

As tissues develop, they are subjected to a variety of mechanical forces. Some of these
forces are instrumental in the development of tissues, while others can result in tissue …

Extracellular matrices (ECMs) are structurally and compositionally diverse networks of
collagenous and noncollagenous glycoproteins, glycosaminoglycans, proteoglycans, and …

Recent advances in computational models of signal propagation and routing in the human
brain have underscored the critical role of white-matter structure. A complementary …

Epithelial sheets are crucial components of all metazoan animals, enclosing organs and
protecting the animal from its environment. Epithelial homeostasis poses unique challenges …

The vertebrate heart tube extends by progressive addition of epithelial second heart field
(SHF) progenitor cells from the dorsal pericardial wall. The interplay between epithelial …

Epithelial structures are foundational for tissue organization in all metazoans. Sheets of
epithelial cells form lateral adhesive junctions and acquire apico-basal polarity …