Total laryngectomy—still cutting-edge?

TK Hoffmann - Cancers, 2021 - mdpi.com
Simple Summary Complete removal of the larynx (total laryngectomy) offers a curative
approach for advanced laryngeal and pharyngeal cancer. If the operation is performed after …

Laser microsurgery versus radiotherapy versus open partial laryngectomy for T2 laryngeal carcinoma: a systematic review of oncological outcomes

F Campo, J Zocchi, M Ralli, D De Seta… - Ear, Nose & Throat …, 2021 - journals.sagepub.com
Introduction: The aim of the current systematic review is to update the pooled survival
outcome of patients with T2 glottic carcinoma treated with either laser surgery (CO2 transoral …

Twenty-year experience with salvage total laryngectomy: lessons learned

N Tsetsos, A Poutoglidis, K Vlachtsis… - The Journal of …, 2021 - cambridge.org
ObjectiveThe purpose of this study was to evaluate the outcome of salvage total
laryngectomy and identify areas for further improvement. MethodA retrospective analysis of …

PD-1 Inhibitors combined with paclitaxel (Albumin-bound) and cisplatin for larynx preservation in locally advanced laryngeal and hypopharyngeal squamous cell …

Q Fang, P Xu, F Cao, D Wu, X Liu - Cancer Immunology, Immunotherapy, 2023 - Springer
Background laryngeal and hypopharyngeal squamous cell carcinoma (SCC) is a common
head and neck cancer with significant impact on quality of life due to its crucial roles in …

Factors predicting pharyngocutaneous fistula in patients after salvage laryngectomy for laryngeal malignancy–a multicenter collaborative cohort study

CWR Fitzgerald, JC Davies, JR de Almeida, JT Rich… - Oral oncology, 2022 - Elsevier
Objectives Pharyngocutaneous fistula (PCF) is a major morbidity of salvage total
laryngectomy (TL). Understanding the factors predicting PCF is fundamental to managing …

Association of pharyngocutaneous fistula with cancer outcomes in patients after laryngectomy: a multicenter collaborative cohort study

JC Davies, S Hugh, JT Rich… - … –Head & Neck …, 2021 - jamanetwork.com
Importance Pharyngocutaneous fistula (PCF) results in an inflammatory reaction, but its
association with the rate of locoregional and distant control, disease-free survival, and …

Elective neck dissection for salvage laryngectomy: a systematic review and meta-analysis

C Lin, SV Puram, MG Bulbul, RK Sethi, JW Rocco… - Oral oncology, 2019 - Elsevier
Objective Elective neck dissection (END) for salvage laryngectomy remains controversial
due to variability in reported occult nodal metastasis rates and postoperative complications …

Salvage surgery for residual or recurrent laryngeal squamous cell carcinoma after (Chemo) radiotherapy: Oncological outcomes and prognostic factors

V Vander Poorten, J Meulemans, JJ Beitler… - European Journal of …, 2021 - Elsevier
Nonsurgical primary treatment of early and advanced laryngeal squamous cell carcinoma,
employing radiotherapy with or without chemotherapy, is considered a standard of care in …

Oncologic outcomes after salvage laryngectomy for squamous cell carcinoma of the larynx and hypopharynx: a multicenter retrospective cohort study

J Meulemans, J Debacker, H Demarsin… - Annals of Surgical …, 2021 - Springer
Objective We aimed to analyze oncologic outcomes and identify patterns of failure and
negative prognostic factors in patients who underwent salvage total laryngectomy (STL) for …

Pectoralis major onlay vs interpositional reconstruction fistulation after salvage total laryngectomy: systematic review and meta-analysis

CI Cabrera, A Joseph Jones… - … –Head and Neck …, 2021 - journals.sagepub.com
Objective To evaluate the difference in pharygocutaneous fistula (PCF) development
between pectoralis major flap onlay and interpositional reconstructions after salvage total …