In just over two decades since the discovery of the first microRNA (miRNA), the field of
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …

MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

Abstract Background Ovarian cancer (OvCa) is one of the most common malignant diseases
of the female reproductive system in the world. The majority of OvCa is diagnosed with …

Ovarian cancer is the most lethal of all gynecologic malignancies and the eighth leading
cause of cancer-related deaths among women worldwide. The main reasons for this poor …

In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …

Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …

MiRNA is a type of small non-coding RNA, by regulating downstream gene expression that
affects the progression of multiple diseases, especially cancer. MiRNA can participate in the …

The predominant way in which conventional chemotherapy kills rapidly proliferating cancer
cells is the induction of DNA damage. However, chemoresistance remains the main obstacle …

The maintenance of genome integrity is essential for any organism survival and for the
inheritance of traits to offspring. To the purpose, cells have developed a complex DNA repair …

High-grade serous ovarian carcinomas (HGSOCs) with BRCA1/2 mutations exhibit
improved outcome and sensitivity to double-strand DNA break (DSB)-inducing agents (ie …